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Postoperative radiotherapy after prostatectomy can be associated with severe side effects.

Edgren, M (author)
Lennernäs, Bo, 1963 (author)
Gothenburg University,Göteborgs universitet,Institutionen för särskilda specialiteter, Avdelningen för onkologi,Institute of Selected Clinical Sciences, Department of Oncology
Häggman, M (author)
Uppsala universitet,Institutionen för kirurgiska vetenskaper,Urology
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Norlén, B J (author)
Uppsala universitet,Institutionen för kirurgiska vetenskaper,Urology
Nilsson, S (author)
Karolinska Institutet
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 (creator_code:org_t)
2001
2001
English.
In: Anticancer research. - 0250-7005. ; 21, s. 2231-
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • This retrospective study was initiated to evaluate the efficacy and side effects of post-prostatectomy external beam radiation therapy (XRT) with a short time interval between surgery and irradiation in patients with prostate adenocarcinoma. Sixteen patients were investigated. The overall results in this study were 3 deaths due to recurring disease and two relapses after an average follow-up of 60 months. Severe side effects were observed. Two patients required surgical intervention due to severe post-radiotherapy side effects. The reason for this could be the high dose delivered to peripheral organs and/or a too short time interval between surgery and postoperative XRT. The results of this study confirmed that postoperative XRT can improve local control frequency in prostate carcinomas. It is recommended that the time interval between surgery and postoperative radiotherapy should to be 3-6 month.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Urologi och njurmedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Urology and Nephrology (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

Keyword

Adenocarcinoma
radiotherapy
surgery
Combined Modality Therapy
Follow-Up Studies
Humans
Male
Prostatectomy
adverse effects
Prostatic Neoplasms
radiotherapy
surgery
Radiotherapy
adverse effects
Retrospective Studies

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ref (subject category)
art (subject category)

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By the author/editor
Edgren, M
Lennernäs, Bo, 1 ...
Häggman, M
Norlén, B J
Nilsson, S
About the subject
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Urology and Neph ...
MEDICAL AND HEALTH SCIENCES
MEDICAL AND HEAL ...
and Clinical Medicin ...
and Cancer and Oncol ...
Articles in the publication
Anticancer resea ...
By the university
University of Gothenburg
Karolinska Institutet
Uppsala University

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