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Patient-reported ge...
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Olsson, Caroline,1970Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology
(author)
Patient-reported genitourinary toxicity for long-term prostate cancer survivors treated with radiation therapy.
- Article/chapterEnglish2013
Publisher, publication year, extent ...
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2013-04-30
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Springer Science and Business Media LLC,2013
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/177912
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https://gup.ub.gu.se/publication/177912URI
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https://doi.org/10.1038/bjc.2013.180DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:126816667URI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Background:The objective of this study is to provide comprehensive overviews of patient-reported urinary symptoms for long-term prostate cancer survivors treated with radiation therapy and for untreated, healthy men.Methods:We performed a population-based cross-sectional study using a study-specific postal questionnaire assessing symptoms among 1007 men consecutively treated at the Sahlgrenska University Hospital, Göteborg, Sweden from 1993-2006 (primary or salvage external beam radiation therapy (EBRT) or EBRT and high-dose rate brachytherapy). We also randomly recruited 350 non-pelvic-irradiated matched control men from the Swedish Total Population Register. Symptom prevalence and prevalence ratios were computed.Results:Survey participation rate was 89% (874/985) for eligible survivors and 73% (243/332) for eligible controls. Median time from treatment to follow-up was 5 years (range, 1-14 years). Among the 21 investigated symptoms reflecting obstruction, frequency, urgency, pain and incontinence, we found significantly higher prevalence compared with controls for 9 symptoms in the EBRT group, 10 in the EBRT+brachytherapy group and 5 in the salvage EBRT group. The prevalence for a majority of the symptoms was stable over time.Conclusion:The presented toxicity profiles provide a thorough understanding of patient-reported urinary symptoms that can assist in developing personalised therapy for prostate cancer.
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Pettersson, N
(author)
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Alsadius, David,1975Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology(Swepub:gu)xalsda
(author)
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Wilderäng, UlricaGothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology(Swepub:gu)xoloul
(author)
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Tucker, S L
(author)
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Johansson, K-A
(author)
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Steineck, Gunnar,1952Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för onkologi,Institute of Clinical Sciences, Department of Oncology(Swepub:gu)xstegu
(author)
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Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för onkologi
(creator_code:org_t)
Related titles
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In:British journal of cancer: Springer Science and Business Media LLC108:10, s. 1964-701532-18270007-0920
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