Cerebrospinal fluid amyloid-β and phenotypic heterogeneity in de novo Parkinson's disease.

• In Parkinson's disease (PD), the motor presentation characterised by postural instability/gait difficulties (PIGD) heralds accelerated motor, functional and cognitive decline, as compared with the more benign tremor-dominant (TD) variant. This makes the PIGD complex an attractive target for the discovery of prognostic biomarkers in PD.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)

Nyckelord

Aged

Amyloid beta-Peptides

cerebrospinal fluid

Brain

pathology

Female

Gait Disorders

Neurologic

etiology

physiopathology

Humans

Magnetic Resonance Imaging

Male

Movement Disorders

etiology

physiopathology

Neuropsychological Tests

Parkinson Disease

cerebrospinal fluid

physiopathology

psychology

Phenotype

Tremor

etiology

physiopathology

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)