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Long-term stimulant...
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Gillberg, Christopher,1950Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för barn- och ungdomspsykiatri,Institute for the Health of Women and Children, Dept of Child and Adolescent Psychiatry
(author)
Long-term stimulant treatment of children with attention-deficit hyperactivity disorder symptoms. A randomized, double-blind, placebo-controlled trial.
- Article/chapterEnglish1997
Publisher, publication year, extent ...
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American Medical Association (AMA),1997
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/182613
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https://gup.ub.gu.se/publication/182613URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:114852535URI
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https://doi.org/10.1001/archpsyc.1997.01830210105014DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-56516URI
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https://lup.lub.lu.se/record/56d40c50-f68d-4a5b-951b-dad8e36dc096URI
Supplementary language notes
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background: We wanted to study the effects of amphetamine on symptoms of attention-deficit hyperactivity disorder (ADHD) over a longer period than has been reported in previous studies of central stimulants in this condition. Methods: Sixty-two children, aged 6 to 11 years, meeting DSM-III-R symptom criteria for ADHD participated in a parallel-group design, randomized, double-blind, placebo-controlled study of amphetamine treatment. Treatment was not restricted to children with "pure" ADHD, ie, some had comorbid diagnoses. In the amphetamine group, children received active treatment for 15 months. Results: Amphetamine was clearly superior to placebo in reducing inattention, hyperactivity, and other disruptive behavior problems and tended to lead to improved results on the Wechsler Intelligence Scale for Children—Revised. Treatment failure rate was considerably lower and time to treatment failure was longer in the amphetamine group. Adverse effects were few and relatively mild. Conclusion: The results of this long-term, placebo-controlled study of the central stimulant amphetamine in the treatment of ADHD indicate that there are remaining positive effects of the drug 15 months after starting treatment.
Subject headings and genre
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MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Psykiatri hsv//swe
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MEDICAL AND HEALTH SCIENCES Clinical Medicine Psychiatry hsv//eng
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Abdominal Pain
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chemically induced
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epidemiology
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Amphetamine
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adverse effects
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therapeutic use
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Attention Deficit Disorder with Hyperactivity
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drug therapy
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psychology
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Bipolar Disorder
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chemically induced
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epidemiology
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Central Nervous System Stimulants
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adverse effects
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therapeutic use
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Child
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Comorbidity
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Double-Blind Method
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Female
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Follow-Up Studies
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Headache
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chemically induced
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epidemiology
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Humans
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Male
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Placebos
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Sleep Disorders
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chemically induced
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epidemiology
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Treatment Outcome
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Wechsler Scales
Added entries (persons, corporate bodies, meetings, titles ...)
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Melander, Hans
(author)
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von Knorring, Anne-LiisUppsala universitet,Institutionen för neurovetenskap,BUP
(author)
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Janols, Lars-OlofUppsala universitet,Institutionen för neurovetenskap,BUP
(author)
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Thernlund, GunillaLund University,Lunds universitet,Barn- och ungdomspsykiatri,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Child and Adolescent Psychiatry,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)pski-gth
(author)
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Hägglöf, Bruno
(author)
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Eidevall-Wallin, Lena
(author)
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Gustafsson, PeikLund University,Lunds universitet,Barn- och ungdomspsykiatri,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Child and Adolescent Psychiatry,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)bup-gpe
(author)
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Kopp, Svenny,1948Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för barn- och ungdomspsykiatri,Institute for the Health of Women and Children, Dept of Child and Adolescent Psychiatry(Swepub:gu)xkopsv
(author)
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EidevallWallin, L
(author)
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Göteborgs universitetInstitutionen för kvinnors och barns hälsa, Avdelningen för barn- och ungdomspsykiatri
(creator_code:org_t)
Related titles
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In:Archives of general psychiatry: American Medical Association (AMA)54, s. 857-0003-990X
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In:Arch Gen Psychiatry: American Medical Association (AMA)54, s. 857-
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