Persistence to antihypertensive drug treatment in Swedish primary healthcare

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: onr:"swepub:oai:gup.ub.gu.se/186289" > Persistence to anti...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Qvarnström, MiriamKarolinska Institutet (author)

Persistence to antihypertensive drug treatment in Swedish primary healthcare

Article/chapterEnglish2013

Publisher, publication year, extent ...

2013-07-16
Springer Science and Business Media LLC,2013

Numbers

LIBRIS-ID:oai:gup.ub.gu.se/186289
https://gup.ub.gu.se/publication/186289URI
https://doi.org/10.1007/s00228-013-1555-zDOI
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-455888URI
http://kipublications.ki.se/Default.aspx?queryparsed=id:127542293URI

Supplementary language notes

Language:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

To determine factors associated with low persistence in patients initiated on drug treatment for hypertension. Cohort study using medical records for patients with hypertension in 48 Swedish primary healthcare centres. Data were linked to national registers on dispensed drugs, hospitalizations, outpatient hospital consultations, deaths, migration, and socioeconomy. We identified 5225 patients (55 % women, mean age 61 years) initiated on antihypertensive drug treatment during 2006-2007. Persistence was measured for two years by the dispensed drugs. Patients with a gap of > 30 days between end of dispensed supply and the next dispensed prescription were classified as non-persistent. This was calculated by Kaplan-Meier analysis. Cox proportional hazard regression was used to estimate hazard ratios for discontinuation. Potential predictors included age, gender, blood pressure before initiation of therapy, cardiovascular comorbidity, educational level, country of birth, and income. Among patients with a dispensed first prescription, 26 % discontinued treatment during the first year, and a further 9 % discontinued during the second year. Discontinuation (all adjusted) was more common in men (P = 0.002) and in younger patients (30-49 years, P < 0.001). Systolic (P < 0.001) but not diastolic blood pressure was positively associated with persistence. Native-born Swedish citizens and patients born in the other Nordic countries had lower discontinuation rates than those born outside the Nordic countries (P < 0.001). Major determinants of discontinuation of antihypertensive drug treatment are male sex, young age, mild-to-moderate systolic blood pressure elevation, and birth outside of Sweden.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Farmakologi och toxikologi hsv//swe
MEDICAL AND HEALTH SCIENCES Basic Medicine Pharmacology and Toxicology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Public Health, Global Health, Social Medicine and Epidemiology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Health Care Service and Management, Health Policy and Services and Health Economy hsv//eng
Drug therapy
Hypertension
Persistence
Primary health care
Blood pressure
Socioeconomy
BLOOD-PRESSURE CONTROL
MEDICATION ADHERENCE
FOLLOW-UP
HYPERTENSION
THERAPY
PRESCRIPTIONS
METAANALYSIS
POPULATION
DATABASE
PREVENTION
Pharmacology (medical)
Epidemiologi

Added entries (persons, corporate bodies, meetings, titles ...)

Kahan, T.Karolinska Institutet (author)
Kieler, H.Karolinska Institutet (author)
Brandt, L. (author)
Hasselstrom, J.Karolinska Institutet (author)
Bostrom, K. B. (author)
Manhem, Karin,1954Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xmanka (author)
Hjerpe, P. (author)
Wettermark, B.Karolinska Institutet (author)
Karolinska InstitutetInstitutionen för medicin, avdelningen för molekylär och klinisk medicin (creator_code:org_t)

Related titles

In:European Journal of Clinical Pharmacology: Springer Science and Business Media LLC69:11, s. 1955-19640031-69701432-1041

Internet link

Find in a library

European Journal of Clinical Pharmacology (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Qvarnström, Miri ...; Kahan, T.; Kieler, H.; Brandt, L.; Hasselstrom, J.; Bostrom, K. B.; show more...; Manhem, Karin, 1 ...; Hjerpe, P.; Wettermark, B.; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Pharmacology and ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Public Health Gl ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Health Care Serv ...

Articles in the publication: European Journal ...

By the university: University of Gothenburg; Uppsala University; Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se