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Heart dysfunction i...
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Holmström, AlexandraGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine
(author)
Heart dysfunction in patients with acute ischemic stroke or TIA does not predict all-cause mortality at long-term follow-up
- Article/chapterEnglish2013
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2013-09-23
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Springer Science and Business Media LLC,2013
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LIBRIS-ID:oai:gup.ub.gu.se/187543
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https://gup.ub.gu.se/publication/187543URI
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https://doi.org/10.1186/1471-2377-13-122DOI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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Background: Despite heart failure being a substantial risk factor for stroke, few studies have evaluated the predictive value of heart dysfunction for all-cause mortality in patients with acute ischemic stroke, in particular in the elderly. The aim of this study was to investigate whether impaired heart function in elderly patients can predict all-cause mortality after acute ischemic stroke or transient ischemic attack (TIA). Methods: A prospective long-term follow-up analysis was performed on a hospital cohort consisting of n = 132 patients with mean age 73 +/- 9 years, presenting with acute ischemic stroke or transient ischemic attack, without atrial fibrillation. All patients were examined by echocardiography during the hospital stay. Data about all-cause mortality were collected at the end of the follow-up period. The mean follow-up period was 56 +/- 22 months. Results: In this cohort, 58% of patients with acute ischemic stroke or TIA had heart dysfunction. Survival analysis showed that heart dysfunction did not predict all-cause mortality in this cohort. Furthermore, in multivariate regression analysis age (HR 5.401, Cl 1.97-14.78, p < 0.01), smoking (HR 3.181, Cl 1.36-7.47, p < 0.01), myocardial infarction (HR 2.826, Cl 1.17-6.83, p < 0.05) were independent predictors of all-cause mortality. Conclusion: In this population with acute ischemic stroke or TIA and without non-valvular atrial fibrillation, impaired heart function does not seem to be a significant predictor of all-cause mortality at long-term follow-up.
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Fu, Michael,1963Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xfumiw
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Hjalmarsson, Clara,1969Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine(Swepub:gu)xhjacl
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Bokemark, Lena,1960Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine(Swepub:gu)xbokle
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Andersson, Björn,1953Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine(Swepub:gu)xandeb
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Göteborgs universitetInstitutionen för medicin, avdelningen för molekylär och klinisk medicin
(creator_code:org_t)
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In:Bmc Neurology: Springer Science and Business Media LLC131471-2377
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