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Effect of alpha-trinositol on secretion induced by Escherichia coli ST-toxin in rat jejunum.
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- Lahti, A-M, 1959 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care
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- Cassuto, Jean (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care
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- Yregård, Liselotte (author)
- Gothenburg University,Göteborgs universitet,Institutionen för de kirurgiska disciplinerna, Avdelningen för anestesiologi och intensivvård,Institute of Surgical Sciences, Department of Anaesthesiology and Intensive Care
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- (creator_code:org_t)
- 2003-12-09
- 2003
- English.
- In: Acta physiologica Scandinavica. - : Wiley. - 0001-6772. ; 179:4, s. 373-9
- Journal article (peer-reviewed)
Abstract
Subject headings
Close
- d-myo-inositol-1,2,6-trisphosphate (alpha-trinositol, PP56), is a synthetic isomer of the intracellular second messenger, d-myo-inositol-1,4,5-trisphospahate. The pharmacological actions of alpha-trinositol include potent anti-inflammatory properties and inhibition of the secretion induced by cholera toxin and obstructive ileus. In the present study, we investigated whether alpha-trinositol was able to influence the secretion induced by heat-stable ST-toxin from Escherichia coli in the rat jejunum.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Anestesi och intensivvård (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Anesthesiology and Intensive Care (hsv//eng)
Keyword
- Animals
- Anti-Inflammatory Agents
- Non-Steroidal
- administration & dosage
- Bacterial Toxins
- pharmacology
- Blood Pressure
- Enterotoxins
- pharmacology
- Infusions
- Intravenous
- Inositol Phosphates
- administration & dosage
- Intestinal Secretions
- drug effects
- Jejunum
- drug effects
- metabolism
- Male
- Rats
- Rats
- Sprague-Dawley
Publication and Content Type
- ref (subject category)
- art (subject category)
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