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- Dobre, D. (author)
Heart rate: a prognostic factor and therapeutic target in chronic heart failure. The distinct roles of drugs with heart rate-lowering properties
- Article/chapterEnglish2014
Publisher, publication year, extent ...
- 2013-12-03
- Wiley,2014
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/189076
- https://gup.ub.gu.se/publication/189076URI
- https://doi.org/10.1093/eurjhf/hft129DOI
Supplementary language notes
- Language:English
Part of subdatabase
- SwePubSwePub
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Notes
- Heart rate not only predicts outcome but may also be a therapeutic target in patients with chronic heart failure. Several classes of pharmacological agents can be used to modulate heart rate, including beta-blockers, ivabradine, digoxin, amiodarone, and verapamil. Choice of agent will depend on heart rhythm, co-morbidities, and disease phenotype. Beneficial and harmful interactions may also exist. The aim of this paper is to summarize the current body of knowledge regarding the relevance of heart rate as a prognostic factor (risk marker) and particularly as a therapeutic target (risk factor) in patients with chronic heart failure, with a special focus on ivabradine, a novel agent that is currently the only available purely bradycardic agent.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
- Heart rate; Heart rate-lowering drugs; Beta-blockers; Ivabradine; Digoxin; Amiodarone; Verapamil; Chronic heart failure
Added entries (persons, corporate bodies, meetings, titles ...)
- Borer, J. S. (author)
- Fox, K. (author)
- Swedberg, Karl,1944Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xsweka (author)
- Adams, K. F. (author)
- Cleland, J. G. (author)
- Cohen-Solal, A. (author)
- Gheorghiade, M. (author)
- Gueyffier, F. (author)
- O'Connor, C. M. (author)
- Fiuzat, M. (author)
- Patak, A. (author)
- Pina, I. L. (author)
- Rosano, G. (author)
- Sabbah, H. N. (author)
- Tavazzi, L. (author)
- Zannad, F. (author)
- Göteborgs universitetInstitutionen för medicin, avdelningen för molekylär och klinisk medicin (creator_code:org_t)
Related titles
- In:European Journal of Heart Failure: Wiley16:1, s. 76-851388-98421879-0844
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- Cohen-Solal, A.
- Gheorghiade, M.
- Gueyffier, F.
- O'Connor, C. M.
- Fiuzat, M.
- Patak, A.
- Pina, I. L.
- Rosano, G.
- Sabbah, H. N.
- Tavazzi, L.
- Zannad, F.
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