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Motor imagery in bi...
Motor imagery in bipolar depression with slowed movement.
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- Liberg, Benny (författare)
- Karolinska Institutet
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- Adler, Mats (författare)
- Karolinska Institutet
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- Jonsson, Tomas (författare)
- Karolinska Institutet
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- Landén, Mikael, 1966 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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- Rahm, Christoffer (författare)
- Karolinska Institutet
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- Wahlund, Lars-Olof (författare)
- Karolinska Institutet
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- Wiberg-Kristoffersen, Maria (författare)
- Karolinska Institutet
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Wahlund, Björn (författare)
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(creator_code:org_t)
- 2013
- 2013
- Engelska.
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Ingår i: The Journal of nervous and mental disease. - 1539-736X. ; 201:10, s. 885-93
- Relaterad länk:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- We hypothesized that motor retardation in bipolar depression is mediated by disruption of the pre-executive stages of motor production. We used functional magnetic resonance imaging to investigate neural activity during motor imagery and motor execution to elucidate whether brain regions that mediate planning, preparation, and control of movement are activated differently in subjects with bipolar depression (n = 9) compared with healthy controls (n = 12). We found significant between-group differences. During motor imagery, the patients activated the posterior medial parietal cortex, the posterior cingulate cortex, the premotor cortex, the prefrontal cortex, and the frontal poles more than the controls did. Activation in the brain areas involved in motor selection, planning, and preparation was altered. In addition, limbic and prefrontal regions associated with self-reference and the default mode network were altered during motor imagery in bipolar depression with motor retardation.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Nyckelord
- Adult
- Aged
- Bipolar Disorder
- complications
- physiopathology
- Cerebrum
- physiology
- physiopathology
- Female
- Functional Neuroimaging
- instrumentation
- methods
- Gyrus Cinguli
- physiology
- physiopathology
- Humans
- Limbic System
- physiology
- physiopathology
- Magnetic Resonance Imaging
- instrumentation
- methods
- Male
- Middle Aged
- Motor Cortex
- physiology
- physiopathology
- Movement
- physiology
- Movement Disorders
- diagnosis
- etiology
- physiopathology
- Parietal Lobe
- physiology
- physiopathology
- Prefrontal Cortex
- physiology
- physiopathology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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