Plasma platelet factor 4: a potentially useful predictor of ischaemic heart disease?

Kutti, JackGothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine (författare)

The aim was to investigate whether plasma platelet factor 4 (PF-4) in suspected acute myocardial infarction (AMI) patients could serve as a prognostic tool and identify patients at risk for future death from AMI or ischaemic heart disease (IHD). Therefore, upon admission to our coronary care unit plasma PF-4 was measured on 109 consecutive patients. 53 of them proved to have AMI, and 50 IHD but no AMI; the remaining 6 had no evidence of IHD. 24 patients died in hospital or during the follow-up period which was an average of 16.7 +/- 2.4 months. The decreased were subgrouped into those dying of AMI (n = 16), and those dying of IHD but with no AMI (n = 8). No deaths from other causes were recorded. As compared with survivors there was a tendency towards higher PF-4 values among those who died of AMI. However, patients who during follow-up suffered death from IHD proved to have significantly (p less than 0.05) higher PF-4 levels than survivors.

Svärdsudd, K (författare)
Sigvaldason, A (författare)
Safai-Kutti, S (författare)
Wadenvik, Hans,1955Gothenburg University,Göteborgs universitet,Medicinska institutionen,Department medicine(Swepub:gu)xwadha (författare)
Göteborgs universitetMedicinska institutionen (creator_code:org_t)

Av författaren/redakt...: Kutti, Jack; Svärdsudd, K; Sigvaldason, A; Safai-Kutti, S; Wadenvik, Hans, ...

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