Rat models reveal differences in cardiocirculatory profile between Takotsubo syndrome and acute myocardial infarction.

Redfors, BjörnGothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory (author)

Takotsubo syndrome, also known as stress-induced cardiomyopathy, is an important differential diagnosis in patients presenting with chest pain and is associated with significant morbidity and mortality. Beyond adrenergic overstimulation the pathophysiology behind Takotsubo is poorly known and the syndrome cannot be differentiated from acute myocardial infarction (AMI) by non-invasive tests. Despite the facts that Takotsubo syndrome and AMI may differ in many important aspects and that potential mechanistic similarities and/or differences between Takotsubo syndrome and AMI have not been established, Takotsubo syndrome patients are treated according to guidelines developed for AMI and acute heart failure. The aim of this article was to assess whether cardiac function and hemodynamic indices differ between rat models of Takotsubo syndrome and AMI.

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kardiologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cardiac and Cardiovascular Systems hsv//eng
acute myocardial infarction; adrenergic stimulation; echocardiography; invasive hemodynamics; stress-induced cardiomyopathy; takotsubo cardiomyopathy

Shao, Yangzhen,1981Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory(Swepub:gu)xshaya (author)
Gasim Elsied, Anwar AliGothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory(Swepub:gu)xgasan (author)
Sun, BoGothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory (author)
Omerovic, Elmir,1968Gothenburg University,Göteborgs universitet,Wallenberglaboratoriet,Wallenberg Laboratory(Swepub:gu)xomeel (author)
Göteborgs universitetWallenberglaboratoriet (creator_code:org_t)

In:Journal of cardiovascular medicine (Hagerstown, Md.)16:9, s. 632-6381558-2035

By the author/editor: Redfors, Björn; Shao, Yangzhen, ...; Gasim Elsied, An ...; Sun, Bo; Omerovic, Elmir, ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cardiac and Card ...

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