Exercise and Dietary Restriction for Promotion of Neurohealth Benefits

• Physical exercise, whether of aerobic, endurance or resistance types, plays a central role in estab-lishing and maintaining the integrity of the brain and central nervous system (CNS). When exer-cise is adhered to in conjunction with selective food/drink intake and dietary restriction it pro-motes neurohealth. In this article, we review the interactions of age and gender, as well as insulin and diabetes, with exercise, individuals’ cognitive-affective status and its interactions with exer-cise propensity. All of which modulate the eventual outcomes of the influence of exercise upon parameters of neurohealth. The combination of exercise with dietary restriction provides nu-merous factors pertaining to psychological, neurochemical and anti-pathological manifestations of neurophysiological resilience even through aging. The challenge evoked by the exercise-diet com-bination in the body mobilizes a multitude of adaptive cellular stress-response signaling pathways in neurons involving neurotrophic factors, anti-inflammatory cytokines, DNA-repair proteins, macroautophagy, and mitochondrial biogenesis.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Health Sciences (hsv//eng)

SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)

SOCIAL SCIENCES  -- Psychology (hsv//eng)

Nyckelord

Exercise; diet; neurohealth; insulin; cognition; affect; brain

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