Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States.

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Wang, Li-San (author)

Rarity of the Alzheimer Disease-Protective APP A673T Variant in the United States.

Article/chapterEnglish2015

Publisher, publication year, extent ...

American Medical Association (AMA),2015

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LIBRIS-ID:oai:gup.ub.gu.se/209908
https://gup.ub.gu.se/publication/209908URI
https://doi.org/10.1001/jamaneurol.2014.2157DOI

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Language:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Recently, a rare variant in the amyloid precursor protein gene (APP) was described in a population from Iceland. This variant, in which alanine is replaced by threonine at position 673 (A673T), appears to protect against late-onset Alzheimer disease (AD). We evaluated the frequency of this variant in AD cases and cognitively normal controls to determine whether this variant will significantly contribute to risk assessment in individuals in the United States.

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Naj, Adam C (author)
Graham, Robert R (author)
Crane, Paul K (author)
Kunkle, Brian W (author)
Cruchaga, Carlos (author)
Murcia, Josue D Gonzalez (author)
Cannon-Albright, Lisa (author)
Baldwin, Clinton T (author)
Zetterberg, Henrik,1973Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xzethe (author)
Blennow, Kaj,1958Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xbleka (author)
Kukull, Walter A (author)
Faber, Kelley M (author)
Schupf, Nicole (author)
Norton, Maria C (author)
Tschanz, Joann T (author)
Munger, Ronald G (author)
Corcoran, Christopher D (author)
Rogaeva, Ekaterina (author)
Lin, Chiao-Feng (author)
Dombroski, Beth A (author)
Cantwell, Laura B (author)
Partch, Amanda (author)
Valladares, Otto (author)
Hakonarson, Hakon (author)
St George-Hyslop, Peter (author)
Green, Robert C (author)
Goate, Alison M (author)
Foroud, Tatiana M (author)
Carney, Regina M (author)
Larson, Eric B (author)
Behrens, Timothy W (author)
Kauwe, John S K (author)
Haines, Jonathan L (author)
Farrer, Lindsay A (author)
Pericak-Vance, Margaret A (author)
Mayeux, Richard (author)
Schellenberg, Gerard D (author)
Albert, Marilyn S (author)
Albin, Roger L (author)
Apostolova, Liana G (author)
Arnold, Steven E (author)
Barber, Robert (author)
Barmada, M Michael (author)
Barnes, Lisa L (author)
Beach, Thomas G (author)
Becker, James T (author)
Beecham, Gary W (author)
Beekly, Duane (author)
Bennett, David A (author)
Bigio, Eileen H (author)
Bird, Thomas D (author)
Blacker, Deborah (author)
Boeve, Bradley F (author)
Bowen, James D (author)
Boxer, Adam (author)
Burke, James R (author)
Buxbaum, Joseph D (author)
Cairns, Nigel J (author)
Cao, Chuanhai (author)
Carlson, Chris S (author)
Carroll, Steven L (author)
Chui, Helena C (author)
Clark, David G (author)
Cribbs, David H (author)
Crocco, Elizabeth A (author)
DeCarli, Charles (author)
DeKosky, Steven T (author)
Demirci, F Yesim (author)
Dick, Malcolm (author)
Dickson, Dennis W (author)
Duara, Ranjan (author)
Ertekin-Taner, Nilufer (author)
Fallon, Kenneth B (author)
Farlow, Martin R (author)
Ferris, Steven (author)
Frosch, Matthew P (author)
Galasko, Douglas R (author)
Ganguli, Mary (author)
Gearing, Marla (author)
Geschwind, Daniel H (author)
Ghetti, Bernardino (author)
Gilbert, John R (author)
Glass, Jonathan D (author)
Graff-Radford, Neill R (author)
Growdon, John H (author)
Hamilton, Ronald L (author)
Hamilton-Nelson, Kara L (author)
Harrell, Lindy E (author)
Head, Elizabeth (author)
Honig, Lawrence S (author)
Hulette, Christine M (author)
Hyman, Bradley T (author)
Jarvik, Gail P (author)
Jicha, Gregory A (author)
Jin, Lee-Way (author)
Jun, Gyungah (author)
Kamboh, M Ilyas (author)
Karydas, Anna (author)
Kaye, Jeffrey A (author)
Kim, Ronald (author)
Koo, Edward H (author)
Kowall, Neil W (author)
Kramer, Joel H (author)
Kramer, Patricia (author)
LaFerla, Frank M (author)
Lah, James J (author)
Leverenz, James B (author)
Levey, Allan I (author)
Li, Ge (author)
Lieberman, Andrew P (author)
Lopez, Oscar L (author)
Lunetta, Kathryn L (author)
Lyketsos, Constantine G (author)
Mack, Wendy J (author)
Marson, Daniel C (author)
Martin, Eden R (author)
Martiniuk, Frank (author)
Mash, Deborah C (author)
Masliah, Eliezer (author)
McCormick, Wayne C (author)
McCurry, Susan M (author)
McDavid, Andrew N (author)
McKee, Ann C (author)
Mesulam, M Marsel (author)
Miller, Bruce L (author)
Miller, Carol A (author)
Miller, Joshua W (author)
Montine, Thomas J (author)
Morris, John C (author)
Murrell, Jill R (author)
Olichney, John M (author)
Parisi, Joseph E (author)
Perry, William (author)
Peskind, Elaine (author)
Petersen, Ronald C (author)
Pierce, Aimee (author)
Poon, Wayne W (author)
Potter, Huntington (author)
Quinn, Joseph F (author)
Raj, Ashok (author)
Raskind, Murray (author)
Reiman, Eric M (author)
Reisberg, Barry (author)
Reitz, Christiane (author)
Ringman, John M (author)
Roberson, Erik D (author)
Rosen, Howard J (author)
Rosenberg, Roger N (author)
Sano, Mary (author)
Saykin, Andrew J (author)
Schneider, Julie A (author)
Schneider, Lon S (author)
Seeley, William W (author)
Smith, Amanda G (author)
Sonnen, Joshua A (author)
Spina, Salvatore (author)
Stern, Robert A (author)
Tanzi, Rudolph E (author)
Thornton-Wells, Tricia A (author)
Trojanowski, John Q (author)
Troncoso, Juan C (author)
Tsuang, Debby W (author)
Van Deerlin, Vivianna M (author)
Van Eldik, Linda J (author)
Vardarajan, Badri N (author)
Vinters, Harry V (author)
Vonsattel, Jean Paul (author)
Weintraub, Sandra (author)
Welsh-Bohmer, Kathleen A (author)
Williamson, Jennifer (author)
Wishnek, Sarah (author)
Woltjer, Randall L (author)
Wright, Clinton B (author)
Younkin, Steven G (author)
Yu, Chang-En (author)
Yu, Lei (author)
Göteborgs universitetInstitutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi (creator_code:org_t)

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In:JAMA neurology: American Medical Association (AMA)72:22168-61572168-6149

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By the author/editor: Wang, Li-San; Naj, Adam C; Graham, Robert R; Crane, Paul K; Kunkle, Brian W; Cruchaga, Carlos; show more...; Murcia, Josue D ...; Cannon-Albright, ...; Baldwin, Clinton ...; Zetterberg, Henr ...; Blennow, Kaj, 19 ...; Kukull, Walter A; Faber, Kelley M; Schupf, Nicole; Norton, Maria C; Tschanz, Joann T; Munger, Ronald G; Corcoran, Christ ...; Rogaeva, Ekateri ...; Lin, Chiao-Feng; Dombroski, Beth ...; Cantwell, Laura ...; Partch, Amanda; Valladares, Otto; Hakonarson, Hako ...; St George-Hyslop ...; Green, Robert C; Goate, Alison M; Foroud, Tatiana ...; Carney, Regina M; Larson, Eric B; Behrens, Timothy ...; Kauwe, John S K; Haines, Jonathan ...; Farrer, Lindsay ...; Pericak-Vance, M ...; Mayeux, Richard; Schellenberg, Ge ...; Albert, Marilyn ...; Albin, Roger L; Apostolova, Lian ...; Arnold, Steven E; Barber, Robert; Barmada, M Micha ...; Barnes, Lisa L; Beach, Thomas G; Becker, James T; Beecham, Gary W; Beekly, Duane; Bennett, David A; Bigio, Eileen H; Bird, Thomas D; Blacker, Deborah; Boeve, Bradley F; Bowen, James D; Boxer, Adam; Burke, James R; Buxbaum, Joseph ...; Cairns, Nigel J; Cao, Chuanhai; Carlson, Chris S; Carroll, Steven ...; Chui, Helena C; Clark, David G; Cribbs, David H; Crocco, Elizabet ...; DeCarli, Charles; DeKosky, Steven ...; Demirci, F Yesim; Dick, Malcolm; Dickson, Dennis ...; Duara, Ranjan; Ertekin-Taner, N ...; Fallon, Kenneth ...; Farlow, Martin R; Ferris, Steven; Frosch, Matthew ...; Galasko, Douglas ...; Ganguli, Mary; Gearing, Marla; Geschwind, Danie ...; Ghetti, Bernardi ...; Gilbert, John R; Glass, Jonathan ...; Graff-Radford, N ...; Growdon, John H; Hamilton, Ronald ...; Hamilton-Nelson, ...; Harrell, Lindy E; Head, Elizabeth; Honig, Lawrence ...; Hulette, Christi ...; Hyman, Bradley T; Jarvik, Gail P; Jicha, Gregory A; Jin, Lee-Way; Jun, Gyungah; Kamboh, M Ilyas; Karydas, Anna; Kaye, Jeffrey A; Kim, Ronald; Koo, Edward H; Kowall, Neil W; Kramer, Joel H; Kramer, Patricia; LaFerla, Frank M; Lah, James J; Leverenz, James ...; Levey, Allan I; Li, Ge; Lieberman, Andre ...; Lopez, Oscar L; Lunetta, Kathryn ...; Lyketsos, Consta ...; Mack, Wendy J; Marson, Daniel C; Martin, Eden R; Martiniuk, Frank; Mash, Deborah C; Masliah, Eliezer; McCormick, Wayne ...; McCurry, Susan M; McDavid, Andrew ...; McKee, Ann C; Mesulam, M Marse ...; Miller, Bruce L; Miller, Carol A; Miller, Joshua W; Montine, Thomas ...; Morris, John C; Murrell, Jill R; Olichney, John M; Parisi, Joseph E; Perry, William; Peskind, Elaine; Petersen, Ronald ...; Pierce, Aimee; Poon, Wayne W; Potter, Huntingt ...; Quinn, Joseph F; Raj, Ashok; Raskind, Murray; Reiman, Eric M; Reisberg, Barry; Reitz, Christian ...; Ringman, John M; Roberson, Erik D; Rosen, Howard J; Rosenberg, Roger ...; Sano, Mary; Saykin, Andrew J; Schneider, Julie ...; Schneider, Lon S; Seeley, William ...; Smith, Amanda G; Sonnen, Joshua A; Spina, Salvatore; Stern, Robert A; Tanzi, Rudolph E; Thornton-Wells, ...; Trojanowski, Joh ...; Troncoso, Juan C; Tsuang, Debby W; Van Deerlin, Viv ...; Van Eldik, Linda ...; Vardarajan, Badr ...; Vinters, Harry V; Vonsattel, Jean ...; Weintraub, Sandr ...; Welsh-Bohmer, Ka ...; Williamson, Jenn ...; Wishnek, Sarah; Woltjer, Randall ...; Wright, Clinton ...; Younkin, Steven ...; Yu, Chang-En; Yu, Lei; show less...

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