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The role of pleiotr...
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Johnsson, MartinLinköpings universitet,Biologi,Tekniska högskolan,AVIAN Behavioural Genomics and Physiology group
(author)
The role of pleiotropy and linkage in genes affecting a sexual ornament and bone allocation in the chicken.
- Article/chapterEnglish2014
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LIBRIS-ID:oai:gup.ub.gu.se/212201
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https://gup.ub.gu.se/publication/212201URI
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https://doi.org/10.1111/mec.12723DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:129000337URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-227274URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-105936URI
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Sexual selection and the ornaments that inform such choices have been extensively studied, particularly from a phenotypic perspective. Although more is being revealed about the genetic architecture of sexual ornaments, much still remains to be discovered. The comb of the chicken is one of the most widely recognized sexual ornaments, which has been shown to be correlated with both fecundity and bone allocation. In this study, we use a combination of multiple intercrosses between White Leghorn populations and wild-derived Red Junglefowl to, first, map quantitative trait loci (QTL) for bone allocation and, second, to identify expression QTL that correlate and colocalize with comb mass. These candidate quantitative genes were then assessed for potential pleiotropic effects on bone tissue and fecundity traits. We identify genes that correlate with both relative comb mass and bone traits suggesting a combination of both pleiotropy and linkage mediates gene regulatory variation in these traits.
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Rubin, Carl-JohanUppsala universitet,Genomik,Department of Medical Biochemistry and Michrobiology, BMC, Uppsala University, Sweden(Swepub:uu)carub021
(author)
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Höglund, AndreyLinköpings universitet,Biologi,Tekniska högskolan,AVIAN Behavioural Genomics and Physiology group(Swepub:liu)andho47
(author)
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Sahlqvist, Anna-StinaUppsala universitet,Autoimmunitet,Research group of Autoimmunity, Akademiska sjukhuset, Uppsala University, Sweden(Swepub:uu)ansah764
(author)
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Jonsson, Kenneth BUppsala universitet,Ortopedi,Department of Surgical Sciences, Orthopaedics, Akademiska sjukhuset, Uppsala university, Sweden(Swepub:uu)kennjons
(author)
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Kerje, SusanneUppsala universitet,Genomik,Research group of Autoimmunity, Akademiska sjukhuset, Uppsala University, Sweden(Swepub:uu)suker516
(author)
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Ekwall, Olov,1968Uppsala universitet,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för pediatrik,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Clinical Sciences, Department of Pediatrics,Institute of Medicine, Department of Rheumatology and Inflammation Research,Autoimmunitet,Research group of Autoimmunity, Akademiska sjukhuset, Uppsala University, Sweden(Swepub:uu)olovekwa
(author)
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Kämpe, OlleUppsala universitet,Karolinska Institutet,Autoimmunitet,Research group of Autoimmunity, Akademiska sjukhuset, Uppsala University, Sweden(Swepub:uu)ollekamp
(author)
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Andersson, LeifUppsala universitet,Genomik,Department of Medical Biochemistry and Microbiology, Uppsala University, Sweden(Swepub:uu)leand227
(author)
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Jensen, Per,1956-Linköpings universitet,Biologi,Tekniska högskolan,AVIAN Behavioural Genomics and Physiology group(Swepub:liu)perje15
(author)
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Wright, Dominic,1977-Linköpings universitet,Biologi,Tekniska högskolan,AVIAN Behavioural Genomics and Physiology group(Swepub:liu)domwr72
(author)
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Linköpings universitetBiologi
(creator_code:org_t)
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In:Molecular ecology: Wiley23:9, s. 2275-861365-294X0962-1083
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Johnsson, Martin
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Rubin, Carl-Joha ...
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Höglund, Andrey
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Sahlqvist, Anna- ...
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Jonsson, Kenneth ...
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Kerje, Susanne
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Ekwall, Olov, 19 ...
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Kämpe, Olle
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Andersson, Leif
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Karolinska Institutet
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