Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients.

Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntington's disease (HD), is at very low levels in CSF and, to our knowledge, has never been measured previously.

Boggio, Roberto (author)
Langbehn, Douglas (author)
Robertson, Nicola (author)
Haider, Salman (author)
Miller, James R C (author)
Zetterberg, Henrik,1973Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry(Swepub:gu)xzethe (author)
Leavitt, Blair R (author)
Kuhn, Rainer (author)
Tabrizi, Sarah J (author)
Macdonald, Douglas (author)
Weiss, Andreas (author)
Göteborgs universitetInstitutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi (creator_code:org_t)

By the author/editor: Wild, Edward J; Boggio, Roberto; Langbehn, Dougla ...; Robertson, Nicol ...; Haider, Salman; Miller, James R ...; show more...; Zetterberg, Henr ...; Leavitt, Blair R; Kuhn, Rainer; Tabrizi, Sarah J; Macdonald, Dougl ...; Weiss, Andreas; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Neurosciences

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