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A highly sensitive novel immunoassay specifically detects low levels of soluble Aβ oligomers in human cerebrospinal fluid.

Yang, Ting (author)
O'Malley, Tiernan T (author)
Kanmert, Daniel (author)
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Jerecic, Jasna (author)
Zieske, Lynn R (author)
Zetterberg, Henrik, 1973 (author)
Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
Hyman, Bradley T (author)
Walsh, Dominic M (author)
Selkoe, Dennis J (author)
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 (creator_code:org_t)
2015-03-22
2015
English.
In: Alzheimer's research & therapy. - : Springer Science and Business Media LLC. - 1758-9193. ; 7:1
  • Journal article (peer-reviewed)
Abstract Subject headings
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  • Amyloid β-protein oligomers play a key role in Alzheimer's disease (AD), but well-validated assays that routinely detect them in cerebrospinal fluid (CSF) are just emerging. We sought to confirm and extend a recent study using the Singulex Erenna platform that reported increased mean CSF oligomer levels in AD.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Basic Medicine -- Neurosciences (hsv//eng)

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