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- Aarnio, K. (författare)
Cancer in Young Adults With Ischemic Stroke
- Artikel/kapitelEngelska2015
Förlag, utgivningsår, omfång ...
- Ovid Technologies (Wolters Kluwer Health),2015
Nummerbeteckningar
- LIBRIS-ID:oai:gup.ub.gu.se/218688
- https://gup.ub.gu.se/publication/218688URI
- https://doi.org/10.1161/strokeaha.115.008694DOI
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- Språk:engelska
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- Background and Purpose-Cancer is a risk factor for ischemic stroke. Little is known about cancer among young adults with ischemic stroke. We studied the frequency of cancer and its association with long-term risk of death among young patients with first-ever ischemic stroke. Methods-1002 patients aged 15 to 49 years, registered in the Helsinki Young Stroke Registry, and with a median follow-up of 10.0 years (interquartile range 6.5-13.8) after stroke were included. Historical and follow-up data were derived from the Finnish Care Register and Statistics Finland. Survival between groups was compared with the Kaplan-Meier life-table method, and Cox proportional hazard models were used to identify factors associated with mortality. Results-One or more cancer diagnosis was made in 77 (7.7%) patients, of whom 39 (3.9%) had cancer diagnosed prestroke. During the poststroke follow-up, 41 (53.2%) of the cancer patients died. Median time from prestroke cancer to stroke was 4.9 (1.0-9.5) years and from stroke to poststroke cancer was 6.7 (2.7-10.9) years. Poststroke cancer was associated with age >40 years, heavy drinking, and cigarette smoking. The cumulative mortality was significantly higher among the cancer patients (68.6%, 95% confidence interval 52.0%-85.3%) compared with patients without cancer (19.7%, 95% confidence interval 16.3%-23.2%). Active cancer at index stroke, melanoma, and lung/respiratory tract cancer had the strongest independent association with death during the follow-up when adjusted for known poststroke mortality prognosticators. Conclusions-Cancer, and especially active cancer and no other apparent cause for stroke, is associated with unfavorable survival among young stroke patients.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Neurovetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Neurosciences hsv//eng
- outcome
- MANIFESTATION
- ASSOCIATION
- PREVENTION
- MORTALITY
- REGISTRY
- THERAPY
- PATTERN
- EVENTS
- Clinical Neurology
- Peripheral Vascular Disease
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Joensuu, H. (författare)
- Haapaniemi, E. (författare)
- Melkas, S. (författare)
- Kaste, M. (författare)
- Tatlisumak, TurgutGothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology(Swepub:gu)xtatlt (författare)
- Putaala, J. (författare)
- Göteborgs universitetInstitutionen för neurovetenskap och fysiologi (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Stroke: Ovid Technologies (Wolters Kluwer Health)46:60039-24991524-4628
Internetlänk
Hitta mer i SwePub
- Av författaren/redakt...
- Aarnio, K.
- Joensuu, H.
- Haapaniemi, E.
- Melkas, S.
- Kaste, M.
- Tatlisumak, Turg ...
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- Putaala, J.
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- Göteborgs universitet
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