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Improving Environme...
Improving Environmental Risk Assessment of Human Pharmaceuticals
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- Ågerstrand, Marlene (author)
- Stockholms universitet,Institutionen för miljövetenskap och analytisk kemi
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- Berg, Cecilia (author)
- Uppsala universitet,Miljötoxikologi
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- Björlenius, Berndt (author)
- KTH,Industriell bioteknologi
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- Breitholtz, Magnus (author)
- Stockholms universitet,Institutionen för miljövetenskap och analytisk kemi
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- Brunström, Björn (author)
- Uppsala universitet,Miljötoxikologi
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- Fick, Jerker, 1971- (author)
- Umeå universitet,Kemiska institutionen
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- Larsson, D. G. Joakim, 1969 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
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- Larsson, D. G. Joakim, 1969 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för infektionssjukdomar,Institute of Biomedicine, Department of Infectious Medicine
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- Sumpter, J. P. (author)
- Uxbridge, United Kingdom
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- Tysklind, Mats, 1956- (author)
- Umeå universitet,Kemiska institutionen
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- Rudén, Christina (author)
- Stockholms universitet,Institutionen för miljövetenskap och analytisk kemi
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(creator_code:org_t)
- 2015-04-16
- 2015
- English.
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In: Environmental Science & Technology. - : American Chemical Society (ACS). - 0013-936X .- 1520-5851. ; 49:9, s. 5336-5345
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Abstract
Subject headings
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- This paper presents 10 recommendations for improving the European Medicines Agency's guidance for environmental risk assessment of human pharmaceutical products. The recommendations are based on up-to-date, available science in combination with experiences from other chemical frameworks such as the REACH-legislation for industrial chemicals. The recommendations concern: expanding the scope of the current guideline; requirements to assess the risk for development of antibiotic resistance; jointly performed assessments; refinement of the test proposal; mixture toxicity assessments on active pharmaceutical ingredients with similar modes of action; use of all available ecotoxicity studies; mandatory reviews; increased transparency; inclusion of emission data from production; and a risk management option. We believe that implementation of our recommendations would strengthen the protection of the environment and be beneficial to society. Legislation and guidance documents need to be updated at regular intervals in order to incorporate new knowledge from the scientific community. This is particularly important for regulatory documents concerning pharmaceuticals in the environment since this is a research field that has been growing substantially in the last decades.
Subject headings
- NATURVETENSKAP -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)
- NATURVETENSKAP -- Biologi -- Ekologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Ecology (hsv//eng)
- NATURVETENSKAP -- Kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmakologi och toxikologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmacology and Toxicology (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Naturresursteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Environmental Engineering (hsv//eng)
- NATURVETENSKAP -- Geovetenskap och miljövetenskap (hsv//swe)
- NATURAL SCIENCES -- Earth and Related Environmental Sciences (hsv//eng)
Keyword
- OCCUPATIONAL-EXPOSURE LIMITS
- AQUATIC ENVIRONMENT
- PRIORITIZING
- PHARMACEUTICALS
- ANTIBIOTIC-RESISTANCE
- ESTROGENIC CHEMICALS
- WATER-POLLUTION
- PUBLIC-HEALTH
- FISH
- MANAGEMENT
- ORGANISMS
- Engineering
- Environmental
- Environmental Sciences
- Occupational-Exposure Limits
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Ågerstrand, Marl ...
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Berg, Cecilia
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Björlenius, Bern ...
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Breitholtz, Magn ...
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Brunström, Björn
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Fick, Jerker, 19 ...
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Larsson, D. G. J ...
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Sumpter, J. P.
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Tysklind, Mats, ...
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Rudén, Christina
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
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and Environmental Sc ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Ecology
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Basic Medicine
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and Pharmacology and ...
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- ENGINEERING AND TECHNOLOGY
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ENGINEERING AND ...
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and Environmental En ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Earth and Relate ...
- Articles in the publication
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Environmental Sc ...
- By the university
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University of Gothenburg
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Royal Institute of Technology
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Umeå University
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Uppsala University
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Stockholm University