Imaging mass spectrometry in neuroscience.

Hanrieder, Jörg,1980Gothenburg University,Göteborgs universitet,National Center for Imaging Mass Spectrometry,Chalmers tekniska högskola,Chalmers University of Technology (författare)

Imaging mass spectrometry is an emerging technique of great potential for investigating the chemical architecture in biological matrices. Although the potential for studying neurobiological systems is evident, the relevance of the technique for application in neuroscience is still in its infancy. In the present Review, a principal overview of the different approaches, including matrix assisted laser desorption ionization and secondary ion mass spectrometry, is provided with particular focus on their strengths and limitations for studying different neurochemical species in situ and in vitro. The potential of the various approaches is discussed based on both fundamental and biomedical neuroscience research. This Review aims to serve as a general guide to familiarize the neuroscience community and other biomedical researchers with the technique, highlighting its great potential and suitability for comprehensive and specific chemical imaging.

Phan, Nhu TN,1981Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,National Center for Imaging Mass Spectrometry,Department of Chemistry and Molecular Biology,University of Gothenburg(Swepub:gu)xphant (författare)
Kurczy, Michael,1980Gothenburg University,Göteborgs universitet,National Center for Imaging Mass Spectrometry,Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)kurczy (författare)
Ewing, Andrew G,1957Gothenburg University,Göteborgs universitet,National Center for Imaging Mass Spectrometry,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology,University of Gothenburg,Chalmers tekniska högskola,Chalmers University of Technology(Swepub:cth)andrewe (författare)
Göteborgs universitetNational Center for Imaging Mass Spectrometry (creator_code:org_t)

Ingår i:ACS chemical neuroscience: American Chemical Society (ACS)4:5, s. 666-791948-7193

Av författaren/redakt...: Hanrieder, Jörg, ...; Phan, Nhu TN, 19 ...; Kurczy, Michael, ...; Ewing, Andrew G, ...

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