SwePub
Sök i LIBRIS databas

  Extended search

WFRF:(Bruun C)
 

Search: WFRF:(Bruun C) > Echocardiographic f...

  • Lauridsen, T. K. (author)

Echocardiographic findings predict in-hospital and 1-year mortality in left-sided native valve Staphylococcus aureus endocarditis: Analysis from the international collaboration on endocarditis-prospective echo cohort study

  • Article/chapterEnglish2015

Publisher, publication year, extent ...

  • 2015

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/227084
  • https://gup.ub.gu.se/publication/227084URI
  • https://doi.org/10.1161/CIRCIMAGING.114.003397DOI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Background: Staphylococcus aureus left-sided native valve infective endocarditis (LNVIE) has higher complication and mortality rates compared with endocarditis from other pathogens. Whether echocardiographic variables can predict prognosis in S aureus LNVIE is unknown. Methods and Results: Consecutive patients with LNVIE, enrolled between January 2000 and September 2006, in the International Collaboration on Endocarditis were identified. Subjects without S aureus IE were matched to those with S aureus IE by the propensity of having S aureus. Survival differences were determined using log-rank significance tests. Independent echocardiographic predictors of mortality were identified using Cox-proportional hazards models that included inverse probability of treatment weighting and surgery as a time-dependent covariate. Of 727 subjects with LNVIE and 1-year follow-up, 202 had S aureus IE. One-year survival rates were significantly lower for patients with S aureus IE overall (57% S aureus IE versus 80% non-S aureus IE; P<0.001) and in the propensity-matched cohort (59% S aureus IE versus 68% non-S aureus IE; P<0.05). Intracardiac abscess (hazard ratio, 2.93; 95% confidence interval, 1.52-5.40; P<0.001) and left ventricular ejection fraction <40% (odds ratio, 3.01; 95% confidence interval, 1.35-6.04; P=0.004) were the only independent echocardiographic predictors of in-hospital mortality in S aureus LNVIE. Valve perforation (hazard ratio, 2.16; 95% confidence interval, 1.21-3.68; P=0.006) and intracardiac abscess (hazard ratio, 2.25; 95% confidence interval, 1.26-3.78; P=0.004) were the only independent predictors of 1-year mortality. Conclusions: S aureus is an independent predictor of 1-year mortality in subjects with LNVIE. In S aureus LNVIE, intracardiac abscess and left ventricular ejection fraction <40% independently predicted in-hospital mortality and intracardiac abscess and valve perforation independently predicted 1-year mortality. © 2015 American Heart Association, Inc.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Park, L. (author)
  • Tong, S. Y. C. (author)
  • Selton-Suty, C. (author)
  • Peterson, G. (author)
  • Cecchi, E. (author)
  • Afonso, L. (author)
  • Habib, G. (author)
  • Paré, C. (author)
  • Tamin, S. (author)
  • Dickerman, S. (author)
  • Bayer, A. S. (author)
  • Johansson, Magnus C,1954Gothenburg University,Göteborgs universitet,Institutionen för medicin,Institute of Medicine(Swepub:gu)xjmagj (author)
  • Chu, V. H. (author)
  • Samad, Z. (author)
  • Bruun, N. E. (author)
  • Fowler, V. G., Jr. (author)
  • Crowley, A. L. (author)
  • Göteborgs universitetInstitutionen för medicin (creator_code:org_t)

Related titles

  • In:Circulation Cardiovascular Imaging8:71941-9651

Internet link

Find in a library

To the university's database

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view