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Rhabdomyoblastic Di...
Rhabdomyoblastic Differentiation in Head and Neck Malignancies Other Than Rhabdomyosarcoma
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Bishop, J. A. (author)
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Thompson, L. D. R. (author)
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Cardesa, A. (author)
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Barnes, L. (author)
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Lewis J.S, , Jr. (author)
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Triantafyllou, A. (author)
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Hellquist, Henrik (author)
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- Stenman, Göran, 1953 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för biomedicin, avdelningen för patologi,Institute of Biomedicine, Department of Pathology
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Hunt, J. L. (author)
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Williams, M. D. (author)
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Slootweg, P. J. (author)
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Devaney, K. O. (author)
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Gnepp, D. R. (author)
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Wenig, B. M. (author)
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Rinaldo, A. (author)
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Ferlito, A. (author)
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(creator_code:org_t)
- 2015-03-11
- 2015
- English.
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In: Head and Neck Pathology. - : Springer Science and Business Media LLC. - 1936-055X .- 1936-0568. ; 9:4, s. 507-518
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Abstract
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- Rhabdomyosarcoma is a relatively common soft tissue sarcoma that frequently affects children and adolescents and may involve the head and neck. Rhabdomyosarcoma is defined by skeletal muscle differentiation which can be suggested by routine histology and confirmed by immunohistochemistry for the skeletal muscle-specific markers myogenin or myoD1. At the same time, it must be remembered that when it comes to head and neck malignancies, skeletal muscle differentiation is not limited to rhabdomyosarcoma. A lack of awareness of this phenomenon could lead to misdiagnosis and, subsequently, inappropriate therapeutic interventions. This review focuses on malignant neoplasms of the head and neck other than rhabdomyosarcoma that may exhibit rhabdomyoblastic differentiation, with an emphasis on strategies to resolve the diagnostic dilemmas these tumors may present. Axiomatically, no primary central nervous system tumors will be discussed. © 2015, Springer Science+Business Media New York.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Keyword
- Head and neck malignancies
- MyoD1
- Myogenin
- Rhabdomyoblastic differentiation
- Rhabdomyosarcoma
- Skeletal muscle differentiation
- Soft tissue sarcomas
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Bishop, J. A.
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Thompson, L. D. ...
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Cardesa, A.
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Barnes, L.
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Lewis J.S, , Jr.
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Triantafyllou, A ...
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show more...
-
Hellquist, Henri ...
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Stenman, Göran, ...
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Hunt, J. L.
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Williams, M. D.
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Slootweg, P. J.
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Devaney, K. O.
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Gnepp, D. R.
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Wenig, B. M.
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Rinaldo, A.
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Ferlito, A.
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Cancer and Oncol ...
- Articles in the publication
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Head and Neck Pa ...
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University of Gothenburg