SwePub
Sök i LIBRIS databas

  Extended search

id:"swepub:oai:gup.ub.gu.se/231730"
 

Search: id:"swepub:oai:gup.ub.gu.se/231730" > Perinatal character...

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist
  • Lindström, UlfGothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research (author)

Perinatal characteristics, older siblings, and risk of ankylosing spondylitis: a case-control study based on national registers

  • Article/chapterEnglish2016

Publisher, publication year, extent ...

  • 2016-01-19
  • Springer Science and Business Media LLC,2016

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/231730
  • https://gup.ub.gu.se/publication/231730URI
  • https://doi.org/10.1186/s13075-016-0917-1DOI
  • https://lup.lub.lu.se/record/8576975URI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-116074URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:132759302URI

Supplementary language notes

  • Language:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Background: The effect of circumstances and exposures early in life on the risk of developing ankylosing spondylitis (AS) is largely unknown. The purpose of this study was to determine whether perinatal characteristics predict development of AS. Methods: AS cases (n = 1960; 59 % men) were defined as listed with a diagnosis of AS at least once in the Swedish National Patient Register and registered in the Swedish Medical Birth Register (born = 1973). Population controls were retrieved from the Swedish Population Register (n = 8378; mean 4.3 controls/case), matched on birth year, sex and county. Odds ratios (OR) for developing AS were determined through conditional logistic regression, with regard to: birth weight, birth order, season of birth, maternal age, gestational length, size for gestational age, type of birth, mode of delivery, congenital malformations, mothers' country of birth, mothers' civil status and size of delivery unit. Results: In the univariate analyses statistically significant increases in risk for developing AS were observed for having older siblings (OR 1.18; 95 % Cl 1.06-1.30). No association was observed for the remainder of analysed exposures, although there was a weak association with birth weight below 3000 g (OR 1.19; 95 % CI 1.04-1.37), though not for "low birth weight" <2500 g (OR 0.90; 95 % CI 0.70-1.16). The increase in risk associated with having older siblings was consistent in a multivariate analysis adjusting for possible confounders (OR 1.23; 95 % Cl 1.09-1.39). The direction and magnitude of the point estimates were also consistent in several sensitivity analyses and when stratifying by sex. Conclusions: Having older siblings was associated with an increased risk for developing AS. These results need to be repeated and confirmed in other cohorts.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Forsblad d'Elia, Helena,1961Umeå universitet,Reumatologi(Swepub:umu)hefo0034 (author)
  • Askling, J.Karolinska Institutet (author)
  • Lie, Elisabeth,1980Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research(Swepub:gu)xlieel (author)
  • Lie, Elisabeth,1980Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research(Swepub:gu)xlieel (author)
  • Exarchou, SofiaLund University,Lunds universitet,Internmedicin - epidemiologi,Forskargrupper vid Lunds universitet,Internal Medicine - Epidemiology,Lund University Research Groups(Swepub:lu)med-seu (author)
  • Jacobsson, Lennart T. H.,1954Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för reumatologi och inflammationsforskning,Institute of Medicine, Department of Rheumatology and Inflammation Research(Swepub:gu)xjacle (author)
  • Kristensen, Lars Erik (author)
  • Göteborgs universitetInstitutionen för medicin, avdelningen för reumatologi och inflammationsforskning (creator_code:org_t)

Related titles

  • In:Arthritis Research & Therapy: Springer Science and Business Media LLC18:161478-63541478-6362

Internet link

Find in a library

To the university's database

  • 1 of 1
  • Previous record
  • Next record
  •    To hitlist

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Close

Copy and save the link in order to return to this view