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A Loss-of-Function ...
A Loss-of-Function Variant in a Minor Isoform of ANK3 Protects Against Bipolar Disorder and Schizophrenia.
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Hughes, Timothy (author)
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Hansson, Lars (author)
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Sønderby, Ida E (author)
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Athanasiu, Lavinia (author)
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Zuber, Verena (author)
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Tesli, Martin (author)
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- Song, Jie (author)
- Karolinska Institutet
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- Hultman, Christina M (author)
- Karolinska Institutet
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- Bergen, Sarah E (author)
- Karolinska Institutet
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- Landén, Mikael, 1966 (author)
- Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för psykiatri och neurokemi,Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry
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Melle, Ingrid (author)
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Andreassen, Ole Andreas (author)
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Djurovic, Srdjan (author)
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(creator_code:org_t)
- Elsevier BV, 2016
- 2016
- English.
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In: Biological psychiatry. - : Elsevier BV. - 1873-2402 .- 0006-3223. ; 80:4, s. 323-330
- Related links:
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Ankyrin-3 (ANK3) was one of the first genes to reach significance in a bipolar disorder genome-wide association study. Many subsequent association studies confirmed this finding and implicated this gene in schizophrenia. However, the exact nature of the role of ANK3 in the pathophysiology remains elusive. In particular, the specific isoforms involved and the nature of the imbalance are unknown.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Psykiatri (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Psychiatry (hsv//eng)
Keyword
- ANK3; Bipolar disorder; Genetics; Minor isoform; Schizophrenia; Splice site
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Hughes, Timothy
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Hansson, Lars
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Sønderby, Ida E
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Athanasiu, Lavin ...
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Zuber, Verena
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Tesli, Martin
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show more...
-
Song, Jie
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Hultman, Christi ...
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Bergen, Sarah E
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Landén, Mikael, ...
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Melle, Ingrid
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Andreassen, Ole ...
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Djurovic, Srdjan
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show less...
- About the subject
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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- MEDICAL AND HEALTH SCIENCES
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MEDICAL AND HEAL ...
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and Clinical Medicin ...
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and Psychiatry
- Articles in the publication
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Biological psych ...
- By the university
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University of Gothenburg
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Karolinska Institutet