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  • Allen, D. B. (author)

GH safety workshop position paper: a critical appraisal of recombinant human GH therapy in children and adults

  • Article/chapterEnglish2016

Publisher, publication year, extent ...

  • Oxford University Press (OUP),2016

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/233288
  • https://gup.ub.gu.se/publication/233288URI
  • https://doi.org/10.1530/eje-15-0873DOI

Supplementary language notes

  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Recombinant human GH (rhGH) has been in use for 30 years, and over that time its safety and efficacy in children and adults has been subject to considerable scrutiny. In 2001, a statement from the GH Research Society (GRS) concluded that 'for approved indications, GH is safe'; however, the statement highlighted a number of areas for on-going surveillance of long-term safety, including cancer risk, impact on glucose homeostasis, and use of high dose pharmacological rhGH treatment. Over the intervening years, there have been a number of publications addressing the safety of rhGH with regard to mortality, cancer and cardiovascular risk, and the need for long-term surveillance of the increasing number of adults who were treated with rhGH in childhood. Against this backdrop of interest in safety, the European Society of Paediatric Endocrinology (ESPE), the GRS, and the Pediatric Endocrine Society (PES) convened a meeting to reappraise the safety of rhGH. The ouput of the meeting is a concise position statement.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Backeljauw, P. (author)
  • Bidlingmaier, M. (author)
  • Biller, B. M. K. (author)
  • Boguszewski, M. (author)
  • Burman, P. (author)
  • Butler, G. (author)
  • Chihara, K. (author)
  • Christiansen, J. (author)
  • Cianfarani, S. (author)
  • Clayton, P. (author)
  • Clemmons, D. (author)
  • Cohen, P. (author)
  • Darendeliler, F. (author)
  • Deal, C. (author)
  • Dunger, D. (author)
  • Erfurth, E. M. (author)
  • Fuqua, J. S. (author)
  • Grimberg, A. (author)
  • Haymond, M. (author)
  • Higham, C. (author)
  • Ho, K. (author)
  • Hoffman, A. R. (author)
  • Hokken-Koelega, A. (author)
  • Johannsson, Gudmundur,1960Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xjgudn (author)
  • Juul, A. (author)
  • Kopchick, J. (author)
  • Lee, P. (author)
  • Pollak, M. (author)
  • Radovick, S. (author)
  • Robison, L. (author)
  • Rosenfeld, R. (author)
  • Ross, R. J. (author)
  • Savendahl, L. (author)
  • Saenger, P. (author)
  • Sorensen, H. T. (author)
  • Stochholm, K. (author)
  • Strasburger, C. (author)
  • Swerdlow, A. (author)
  • Thorner, M. (author)
  • Göteborgs universitetInstitutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition (creator_code:org_t)

Related titles

  • In:European Journal of Endocrinology: Oxford University Press (OUP)174:20804-46431479-683X

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