Multigrowth Factor Delivery via Immobilization of Gene Therapy Vectors

• Molecules can be immobilized onto biomaterials by a chemical vapor deposition (CVD) coating strategy. Pentafluorophenolester groups react with amine side chains on antibodies, which can selectively immobilize adenoviral vectors for gene delivery of growth factors. These vectors can produce functional proteins within defined regions of biomaterials to produce customizable structures for targeted tissue regeneration.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine (hsv//eng)

Nyckelord

bone morphogenetic protein-7

in-vitro

scaffolds

osseointegration

differentiation

microparticles

regeneration

ligament

defects

vivo

Chemistry

Science & Technology - Other Topics

Materials Science

Physics

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)