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- Aarnio, K. (author)
Cardiovascular events after ischemic stroke in young adults: A prospective follow-up study
- Article/chapterEnglish2016
Publisher, publication year, extent ...
- 2016-04-20
- Ovid Technologies (Wolters Kluwer Health),2016
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/238445
- https://gup.ub.gu.se/publication/238445URI
- https://doi.org/10.1212/wnl.0000000000002689DOI
Supplementary language notes
- Language:English
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Notes
- Objectives:To study the long-term risk of recurrent cardiac, arterial, and venous events in young stroke patients, and whether these risks differed between etiologic subgroups.Methods:The study population comprised 970 patients aged 15-49 years from the Helsinki Young Stroke Registry (HYSR) who had an ischemic stroke in 1994-2007. We obtained follow-up data until 2012 from the Finnish Care Register and Statistics Finland. Cumulative 15-year risks were analyzed with life tables, whereas relative risks and corresponding confidence intervals (CI) were based on hazard ratios (HR) from Cox regression analyses.Results:There were 283 (29.2%) patients with a cardiovascular event during the median follow-up of 10.1 years (range 0.1-18.0). Cumulative 15-year risk for venous events was 3.9%. Cumulative 15-year incidence rate for composite vascular events was 34.0 (95% CI 30.1-38.2) per 1,000 person-years. When adjusted for age and sex, patients with an index stroke caused by high-risk sources of cardioembolism had the highest HR for any subsequent cardiovascular events (3.7; 95% CI 2.6-5.4), whereas the large-artery atherosclerosis group had the highest HR (2.7; 95% CI 1.6-4.6) for recurrent stroke compared with patients with stroke of undetermined etiology.Conclusions:The risk for future cardiovascular events after ischemic stroke in young adults remains high for years after the index stroke, in particular when the index stroke is caused by high-risk sources of cardioembolism or large-artery atherosclerosis.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Neurovetenskaper hsv//swe
- MEDICAL AND HEALTH SCIENCES Basic Medicine Neurosciences hsv//eng
- HOSPITAL DISCHARGE REGISTER
- RECURRENT VASCULAR EVENTS
- LONG-TERM
- PROGNOSIS
- ATHEROSCLEROTIC DISEASE
- VENOUS THROMBOEMBOLISM
- RISK
- POPULATION
- DEATH
- AGE
- CLASSIFICATION
Added entries (persons, corporate bodies, meetings, titles ...)
- Siegerink, B. (author)
- Pirinen, J. (author)
- Sinisalo, J. (author)
- Lehto, M. (author)
- Haapaniemi, E. (author)
- Nave, A. H. (author)
- Kaste, M. (author)
- Tatlisumak, TurgutGothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology(Swepub:gu)xtatlt (author)
- Putaala, J. (author)
- Göteborgs universitetInstitutionen för neurovetenskap och fysiologi (creator_code:org_t)
Related titles
- In:Neurology: Ovid Technologies (Wolters Kluwer Health)86:20, s. 1872-18790028-38781526-632X
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