WFRF:(Biller Beverly M K)
Sökning: WFRF:(Biller Beverly M K) > (2015-2019) > Exploring Inpatient...
- Stewart, Paul M (författare)
Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency.
- Artikel/kapitelEngelska2016
Förlag, utgivningsår, omfång ...
- 2016-09-13
- The Endocrine Society,2016
Nummerbeteckningar
- LIBRIS-ID:oai:gup.ub.gu.se/246210
- https://gup.ub.gu.se/publication/246210URI
- https://doi.org/10.1210/jc.2016-2221DOI
Kompletterande språkuppgifter
- Språk:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- Patients with adrenal insufficiency (AI) (primary AI [PAI], secondary AI due to a pituitary disorder [PIT] and congenital adrenal hyperplasia [CAH]) have reduced life expectancy; however, the underlying explanation remains unknown.To evaluate characteristics, comorbidities, and hospitalizations in AI patients.Retrospective observational.Using a United States-based national payer database comprising of more than 108 million members, strict inclusion criteria including diagnostic codes and steroid prescription records were used to identify 10 383 adults with AI; 1014 with PAI, 8818 with PIT, and 551 with CAH. Patients were matched 1:1 to controls, based on age (±5 y), gender, insurance, and region and followed for more than 12 months.None.Demographic variables, comorbidities (diabetes mellitus [DM] types 1 and 2, depression, anxiety, hyperlipidemia, hypertension) and hospitalization incidence.Compared with controls, patients with AI had higher odds of DM, hypertension, hyperlipidaemia, depression, and anxiety, ranging from an odds ratio (OR) of 1.51 for hyperlipidaemia in PAI to 3.85 for DM in CAH. Odds of having DM (OR, 3.85; 95% confidence interval, 2.52-5.90) or anxiety (OR, 2.99; 95% confidence interval, 2.02-4.42) compared with controls were highest in CAH, whereas depression was highest in PAI and PIT (OR, 2.40 and 2.55). ORs of hyperlipidaemia and hypertension (OR, 1.98 and 2.24) were highest in the PIT cohort. Inpatient admissions were more frequent in PAI (4.64:1; P < .0001) and PIT (4.00:1; P < .0001) than controls; infection was the most common cause for admission.Patients with AI carry a significant metabolic and psychiatric burden, with higher risk of comorbidities and hospital admissions than matched controls.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Endokrinologi och diabetes hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Endocrinology and Diabetes hsv//eng
- Adrenal insufficiency
- hypopituitarism
- congenital adrenal hyperplasia
- Addison's disease
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Biller, Beverly M K (författare)
- Marelli, Claudio (författare)
- Gunnarsson, Candace (författare)
- Ryan, Michael P (författare)
- Johannsson, Gudmundur,1960Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition(Swepub:gu)xjgudn (författare)
- Göteborgs universitetInstitutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition (creator_code:org_t)
Sammanhörande titlar
- Ingår i:The Journal of clinical endocrinology and metabolism: The Endocrine Society101:12, s. 4843-48501945-71970021-972X
Internetlänk
Hitta via bibliotek
- The Journal of clinical endocrinology and metabolism (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
Hitta mer i SwePub
- Av författaren/redakt...
- Stewart, Paul M
- Biller, Beverly ...
- Marelli, Claudio
- Gunnarsson, Cand ...
- Ryan, Michael P
- Johannsson, Gudm ...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
- MEDICIN OCH HÄLS ...
- och Klinisk medicin
- och Endokrinologi oc ...
- Artiklar i publikationen
- The Journal of c ...
- Av lärosätet
- Göteborgs universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
