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Nebulised racemic a...
Nebulised racemic adrenaline in the treatment of acute bronchiolitis in infants and toddlers.
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- Kristjánsson, Sigurdur, 1955 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
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Lødrup Carlsen, K C (author)
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- Wennergren, Göran, 1947 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
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- Strannegård, Inga-Lisa, 1937 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kvinnors och barns hälsa, Avdelningen för pediatrik,Institute for the Health of Women and Children, Dept of Paediatrics
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Carlsen, K H (author)
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(creator_code:org_t)
- 1993
- 1993
- English.
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In: Archives of disease in childhood. - 1468-2044. ; 69:6, s. 650-4
- Related links:
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https://gup.ub.gu.se...
Abstract
Subject headings
Close
- The effect of inhaled nebulised racemic adrenaline upon symptoms of acute bronchiolitis was investigated in 29 infants and toddlers aged 2-17.5 months by transcutaneous oxygen tension (TcPO2), oxygen saturation, transcutaneous carbon dioxide tension (TcPCO2), and clinical evaluation in a double blind placebo controlled study. Clinical score and TcPO2 improved significantly at 30, 45, and 60 minutes after inhalation of racemic adrenaline, with an increase in TcPO2 > or = 0.5 kPa in 72% of the children < 1 year of age. No significant improvement was observed after inhalation of placebo. No significant changes in heart rate or TcPCO2 were observed from before to after inhalation, but a small increase in mean systolic blood pressure was observed immediately and 45 minutes after racemic adrenaline inhalation. This study demonstrates that treatment with nebulised racemic adrenaline improved oxygenation and clinical signs in hospitalised children aged less than 18 months with bronchiolitis.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Pediatrik (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Pediatrics (hsv//eng)
Keyword
- Acute Disease
- Administration
- Inhalation
- Blood Gas Monitoring
- Transcutaneous
- Blood Pressure
- drug effects
- Bronchiolitis
- blood
- drug therapy
- Epinephrine
- administration & dosage
- Female
- Humans
- Infant
- Male
- Racepinephrine
- Time Factors
Publication and Content Type
- ref (subject category)
- art (subject category)
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