Search: WFRF:(Nyandoro Stephen S. 1975)
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Flavonoids from Ery...
Flavonoids from Erythrina schliebenii
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- Nyandoro, Stephen S., 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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- Munissi, Joan J. E., 1976 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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Kombo, M. (author)
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Mgina, C. A. (author)
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Pan, F. F. (author)
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- Gruhonjic, Amra (author)
- Gothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center
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- Fitzpatrick, Paul A. (author)
- Gothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center
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Lu, Y. (author)
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Wang, B. (author)
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Rissanen, K. (author)
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- Erdelyi, Mate, 1975 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Svenskt NMR-centrum vid Göteborgs universitet,Department of Chemistry and Molecular Biology,Swedish NMR Centre at Göteborg University,organisk kemi
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(creator_code:org_t)
- 2017-01-23
- 2017
- English.
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In: Journal of Natural Products. - : American Chemical Society (ACS). - 0163-3864 .- 1520-6025. ; 80:2, s. 377-383
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
Subject headings
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- Prenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2-4), and nineteen known natural products (5-23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32-64 mu g mL(-1) and 36.9-101.8 mu M, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0-290.6 mu M (pure compounds) and 38.3 to >100 mu g mL(-1) (crude extracts). RAMSON D, 1973, PHYTOCHEMISTRY, V12, P2211
Subject headings
- NATURVETENSKAP -- Biologi -- Biokemi och molekylärbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Biochemistry and Molecular Biology (hsv//eng)
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Keyword
- stem bark
- caffra thunb
- pterocarpan
- isoflavanones
- isoflavones
- orientalis
- addisoniae
- sacleuxii
- tanzania
- Plant Sciences
- Pharmacology & Pharmacy
Publication and Content Type
- ref (subject category)
- art (subject category)
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- By the author/editor
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Nyandoro, Stephe ...
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Munissi, Joan J. ...
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Kombo, M.
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Mgina, C. A.
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Pan, F. F.
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Gruhonjic, Amra
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show more...
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Fitzpatrick, Pau ...
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Lu, Y.
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Wang, B.
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Rissanen, K.
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Erdelyi, Mate, 1 ...
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- About the subject
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Biochemistry and ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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and Organic Chemistr ...
- Articles in the publication
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Journal of Natur ...
- By the university
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University of Gothenburg
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Uppsala University