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Flavonoids from Ery...
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Nyandoro, Stephen S.,1975Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
(author)
Flavonoids from Erythrina schliebenii
- Article/chapterEnglish2017
Publisher, publication year, extent ...
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2017-01-23
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American Chemical Society (ACS),2017
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/251648
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https://gup.ub.gu.se/publication/251648URI
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https://doi.org/10.1021/acs.jnatprod.6b00839DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-355956URI
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Prenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2-4), and nineteen known natural products (5-23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32-64 mu g mL(-1) and 36.9-101.8 mu M, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0-290.6 mu M (pure compounds) and 38.3 to >100 mu g mL(-1) (crude extracts). RAMSON D, 1973, PHYTOCHEMISTRY, V12, P2211
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Munissi, Joan J. E.,1976Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology
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Kombo, M.
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Mgina, C. A.
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Pan, F. F.
(author)
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Gruhonjic, AmraGothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center
(author)
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Fitzpatrick, Paul A.Gothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center(Swepub:gu)xfitpa
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Lu, Y.
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Wang, B.
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Rissanen, K.
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Erdelyi, Mate,1975Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Svenskt NMR-centrum vid Göteborgs universitet,Department of Chemistry and Molecular Biology,Swedish NMR Centre at Göteborg University,organisk kemi(Swepub:uu)mateerde
(author)
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Göteborgs universitetInstitutionen för kemi och molekylärbiologi
(creator_code:org_t)
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In:Journal of Natural Products: American Chemical Society (ACS)80:2, s. 377-3830163-38641520-6025
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Nyandoro, Stephe ...
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Munissi, Joan J. ...
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Kombo, M.
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Mgina, C. A.
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Pan, F. F.
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Gruhonjic, Amra
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Fitzpatrick, Pau ...
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Lu, Y.
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Wang, B.
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Rissanen, K.
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Erdelyi, Mate, 1 ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Biological Scien ...
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and Biochemistry and ...
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- NATURAL SCIENCES
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NATURAL SCIENCES
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and Chemical Science ...
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Journal of Natur ...
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University of Gothenburg
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Uppsala University