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  • Nyandoro, Stephen S.,1975Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology (author)

Flavonoids from Erythrina schliebenii

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2017-01-23
  • American Chemical Society (ACS),2017

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/251648
  • https://gup.ub.gu.se/publication/251648URI
  • https://doi.org/10.1021/acs.jnatprod.6b00839DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-355956URI

Supplementary language notes

  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Prenylated and O-methylflavonoids including one new pterocarpan (1), three new isoflavones (2-4), and nineteen known natural products (5-23) were isolated and identified from the root, stem bark, and leaf extracts of Erythrina schliebenii. The crude extracts and their constituents were evaluated for antitubercular activity against Mycobacterium tuberculosis (H37Rv strain), showing MICs of 32-64 mu g mL(-1) and 36.9-101.8 mu M, respectively. Evaluation of their toxicity against the aggressive human breast cancer cell line MDA-MB-231 indicated EC50 values of 13.0-290.6 mu M (pure compounds) and 38.3 to >100 mu g mL(-1) (crude extracts). RAMSON D, 1973, PHYTOCHEMISTRY, V12, P2211

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Munissi, Joan J. E.,1976Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology (author)
  • Kombo, M. (author)
  • Mgina, C. A. (author)
  • Pan, F. F. (author)
  • Gruhonjic, AmraGothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center (author)
  • Fitzpatrick, Paul A.Gothenburg University,Göteborgs universitet,Sahlgrenska Cancer Center(Swepub:gu)xfitpa (author)
  • Lu, Y. (author)
  • Wang, B. (author)
  • Rissanen, K. (author)
  • Erdelyi, Mate,1975Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Svenskt NMR-centrum vid Göteborgs universitet,Department of Chemistry and Molecular Biology,Swedish NMR Centre at Göteborg University,organisk kemi(Swepub:uu)mateerde (author)
  • Göteborgs universitetInstitutionen för kemi och molekylärbiologi (creator_code:org_t)

Related titles

  • In:Journal of Natural Products: American Chemical Society (ACS)80:2, s. 377-3830163-38641520-6025

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