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Incidence and outco...
Incidence and outcome of surgery for adult hydrocephalus patients in Sweden
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- Sundström, Nina (författare)
- Umeå universitet,Umeå University,Umea Univ, Dept Radiat Sci, Biomed Engn, Umea, Sweden.,Institutionen för strålningsvetenskaper,Umeå University, Sweden
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- Malm, Jan (författare)
- Umeå universitet,Umeå University,Umea Univ, Dept Pharmacol & Clin Neurosci, Umea, Sweden.,Klinisk neurovetenskap,Umeå University, Sweden
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- Laurell, Katarina (författare)
- Umeå universitet,Umeå University,Umea Univ, Dept Pharmacol & Clin Neurosci, Umea, Sweden.,Klinisk neurovetenskap,Umeå University, Sweden
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- Lundin, Fredrik (författare)
- Linköpings universitet,Linköping University,Linkoping Univ, Dept Clin & Expt Med, Linkoping, Sweden.,Avdelningen för neuro- och inflammationsvetenskap,Medicinska fakulteten,Region Östergötland, Neurologiska kliniken i Linköping
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- Kahlon, Babar (författare)
- Lund University,Lunds universitet,Neurokirurgi,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurosurgery,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine,Skåne University Hospital,Univ Hosp, Dept Neurosurg, Lund, Sweden.,Lund University Hospital, Sweden
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- Cesarini, Kristina G. (författare)
- Uppsala universitet,Uppsala University,Neurokirurgi,Uppsala University, Sweden
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- Leijon, Göran (författare)
- Linköpings universitet,Linköping University,Linkoping Univ, Dept Clin & Expt Med, Linkoping, Sweden.,Neurologi,Medicinska fakulteten,Region Östergötland, Neurologiska kliniken i Linköping
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- Wikkelsö, Carsten, 1947 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Univ Gothenburg, Inst Neurosci & Physiol, Gothenburg, Sweden.,University of Gothenburg, Sweden
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Umeå University Umea Univ, Dept Radiat Sci, Biomed Engn, Umea, Sweden (creator_code:org_t)
- 2016-09-13
- 2017
- Engelska.
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Ingår i: British Journal of Neurosurgery. - : Informa UK Limited. - 0268-8697 .- 1360-046X. ; 31:1, s. 21-27
- Relaterad länk:
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http://dx.doi.org/10...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- Object: To present population-based and age related incidence of surgery and clinical outcome for adult patients operated for hydrocephalus, registered in the Swedish Hydrocephalus Quality Registry (SHQR). Methods: All patients registered in SHQR during 2004-2011 were included. Data on age, gender, type of hydrocephalus and type of surgery were extracted as well as three months outcome for patients with idiopathic normal pressure hydrocephalus (iNPH). Results: The material consisted of 2360 patients, 1229 men and 1131 women, age 63.8 +/- 14.4 years (mean standard deviation (SD)). The mean total incidence of surgery was 5.1 +/- 0.9 surgeries/100,000/year; 4.7 +/- 0.9 shunt surgeries and 0.4 +/- 0.1 endoscopic third ventriculostomies. For iNPH, secondary communicating hydrocephalus and obstructive hydrocephalus, the incidence of surgery was 2.2 +/- 0.8, 1.9 +/- 0.3 and 0.8 +/- 0.1/100,000/year, respectively. During 2004-2011, the incidence of surgery increased in total (p = .044), especially in age groups 70-79 years and > 80 years (p = .012 and p = .031). After surgery, 253 of 652 iNPH patients (38.8%) improved at least one step on the modified Rankin scale (mRS). Number needed to treat was 3.0 for improving one patient from unfavourable (mRS 3-5) to favourable (mRS 0-2). The mean score of a modified iNPH scale increased from 54 +/- 23 preoperatively to 63 +/- 25 postoperatively (p < .0001, n = 704), and 58% improved. No significant regional differences in incidence, surgical techniques or outcome were found. Conclusions: Incidence of hydrocephalus surgery increased significantly during 2004-2011, specifically in elderly patients. Surgical treatment of INPH markedly improved functional independence, but the improvement rate was low compared to recent single- and multicentre studies. Thus, the potential for surgical improvement is likely lower than generally reported when treating patients as part of everyday clinical care.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
Nyckelord
- Hydrocephalus
- normal pressure
- surgical incidence
- clinical outcome
- hydrocephalus quality registry
- population based
- normal-pressure hydrocephalus
- inph
- multicenter
- prevalence
- Neurosciences & Neurology
- Surgery
- Hydrocephalus
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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