The role of cholesterol metabolism and various steroid abnormalities in autism spectrum disorders: A hypothesis paper

Gillberg, Christopher,1950Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre (author)

Based on evidence from the relevant research literature, we present a hypothesis that there may be a link between cholesterol, vitamin D, and steroid hormones which subsequently impacts on the development of at least some of the autisms [Coleman & Gillberg]. Our hypothesis, driven by the peer reviewed literature, posits that there may be links between cholesterol metabolism, which we will refer to as steroid metabolism and findings of steroid abnormalities of various kinds (cortisol, testosterone, estrogens, progesterone, vitamin D) in autism spectrum disorder (ASD). Further research investigating these potential links is warranted to further our understanding of the biological mechanisms underlying ASD. Autism Res2017. (c) 2017 The Authors Autism Research published by Wiley Periodicals, Inc. on behalf of International Society for Autism Research. Autism Res 2017, 10: 1022-1044. (c) 2017 International Society for Autism Research, Wiley Periodicals, Inc.

MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Neurovetenskaper hsv//swe
MEDICAL AND HEALTH SCIENCES Basic Medicine Neurosciences hsv//eng
autism
cholesterol
cortisol
estrogens
steroid hormones
testosterone
vitamin D
LEMLI-OPITZ-SYNDROME
CORTISOL CIRCADIAN-RHYTHMS
MALE BRAIN THEORY
VITAMIN-D
TUBEROUS SCLEROSIS
INTRANASAL OXYTOCIN
FUNCTIONING
CHILDREN
SYSTEMATIC REVIEWS
SALIVARY CORTISOL
PRISMA STATEMENT

Fernell, Elisabeth,1948Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre(Swepub:gu)xferne (author)
Kočovská, Eva,1962Gothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre (author)
Minnis, HelenGothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre(Swepub:gu)xminnh (author)
Bourgeron, T. (author)
Thompson, LucyGothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre(Swepub:gu)xtholy (author)
Allely, Clare SarahGothenburg University,Göteborgs universitet,Gillbergcentrum,Gillberg Neuropsychiatry Centre (author)
Göteborgs universitetGillbergcentrum (creator_code:org_t)

By the author/editor: Gillberg, Christ ...; Fernell, Elisabe ...; Kočovská, Eva, 1 ...; Minnis, Helen; Bourgeron, T.; Thompson, Lucy; show more...; Allely, Clare Sa ...; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Neurosciences

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