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Long-term exposure to low-level air pollution and greenness and mortality in Northern Europe. The Life-GAP project

Xu, S. S. (författare)
Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway,Univ Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway.
Marcon, A. (författare)
Unit of Epidemiology and Medical Statistics, Department of Diagnostics and Public Health, University of Verona, Verona, Italy,Univ Verona, Dept Diagnost & Publ Hlth, Unit Epidemiol & Med Stat, Verona, Italy.
Bertelsen, R. J. (författare)
Department of Clinical Science, University of Bergen, Bergen, Norway,Univ Bergen, Dept Clin Sci, Bergen, Norway.
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Benediktsdottir, B. (författare)
Department of Respiratory Medicine and Sleep, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland,Landspitali Natl Univ Hosp Iceland, Dept Resp Med & Sleep, Reykjavik, Iceland.
Brandt, J. (författare)
Department of Environmental Science, Aarhus University, Roskilde, Denmark,Aarhus Univ, Dept Environm Sci, Roskilde, Denmark.
Engemann, K. (författare)
Section for Ecoinformatics & Biodiversity, Department of Bioscience, Aarhus University, Aarhus C, Denmark,Aarhus Univ, Dept Biosci, Sect Ecoinformat & Biodivers, Aarhus, Denmark.
Modig, Lars (författare)
Umeå universitet,Avdelningen för hållbar hälsa,Umeå Univ, Dept Publ Hlth & Clin Med, Sect Sustainable Hlth, Umeå, Sweden.
Geels, C. (författare)
Department of Environmental Science, Aarhus University, Roskilde, Denmark,Aarhus Univ, Dept Environm Sci, Roskilde, Denmark.
Gislason, T. (författare)
Department of Respiratory Medicine and Sleep, Landspitali – the National University Hospital of Iceland, Reykjavik, Iceland,Landspitali Natl Univ Hosp Iceland, Dept Resp Med & Sleep, Reykjavik, Iceland.
Heinrich, J. (författare)
Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, Ludwig Maximilian University of Munich, Munich, Germany; Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia,Ludwig Maximilian Univ Munich, Univ Hosp, Inst & Clin Occupat Social & Environm Med, Munich, Germany.;Univ Melbourne, Melbourne Sch Populat & Global Hlth, Allergy & Lung Hlth Unit, Melbourne, Australia.
Holm, Mathias, 1969 (författare)
Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för samhällsmedicin och folkhälsa,Institute of Medicine, School of Public Health and Community Medicine,Occupational and Environmental Medicine, School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden,Univ Gothenburg, Inst Med Sahlgrenska Acad, Sch Publ Hlth & Community Med, Occupat & Environm Med, Gothenburg, Sweden.
Janson, Christer (författare)
Uppsala universitet,Lung- allergi- och sömnforskning
Markevych, I. (författare)
Institute of Psychology, Jagiellonian University, Krakow, Poland,Jagiellonian Univ, Inst Psychol, Krakow, Poland.
Modig, L. (författare)
Orru, H. (författare)
Department of Public Health, Institute of Family Medicine and Public Health, Faculty of Medicine, University of Tartu, Tartu, Estonia,Univ Tartu, Inst Family Med & Publ Hlth, Fac Med, Dept Publ Hlth, Tartu, Estonia.
Schlünssen, V. (författare)
Department of Public Health, Research Unit for Environment Occupation and Health, Danish Ramazzini Center, Aarhus University, Aarhus, Denmark,Aarhus Univ, Danish Ramazzini Ctr, Dept Publ Hlth, Res Unit Environm Occupat & Hlth, Aarhus, Denmark.
Sigsgaard, T. (författare)
Department of Public Health, Research Unit for Environment Occupation and Health, Danish Ramazzini Center, Aarhus University, Aarhus, Denmark,Aarhus Univ, Danish Ramazzini Ctr, Dept Publ Hlth, Res Unit Environm Occupat & Hlth, Aarhus, Denmark.
Johannessen, A. (författare)
Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway,Univ Bergen, Dept Global Publ Hlth & Primary Care, Bergen, Norway.
Frohn, Lise Marie (författare)
Aarhus Univ, Dept Environm Sci, Roskilde, Denmark.
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Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway Univ Bergen, Ctr Int Hlth, Dept Global Publ Hlth & Primary Care, Bergen, Norway (creator_code:org_t)
Elsevier, 2023
2023
Engelska.
Ingår i: Environment International. - : Elsevier. - 0160-4120 .- 1873-6750. ; 181
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • Background: Air pollution has been linked to mortality, but there are few studies examining the association with different exposure time windows spanning across several decades. The evidence for the effects of green space and mortality is contradictory.Objective: We investigated all-cause mortality in relation to exposure to particulate matter (PM2.5 and PM10), black carbon (BC), nitrogen dioxide (NO2), ozone (O3) and greenness (normalized difference vegetation index NDVI) across different exposure time windows.Methods: The exposure assessment was based on a combination of the Danish Eulerian Hemispheric Model and the Urban Background Model for the years 1990, 2000 and 2010. The analysis included a complete case dataset with 9,135 participants from the third Respiratory Health in Northern Europe study (RHINE III), aged 40-65 years in 2010, with mortality follow-up to 2021. We performed Cox proportional hazard models, adjusting for potential confounders.Results: Altogether, 327 (3.6 %) persons died in the period 2010-2021. Increased exposures in 1990 of PM2.5, PM10, BC and NO2 were associated with increased all-cause mortality hazard ratios of 1.40 (95 % CI1.04-1.87 per 5 mu g/m3), 1.33 (95 % CI: 1.02-1.74 per 10 mu g/m3), 1.16 (95 % CI: 0.98-1.38 per 0.4 mu g/m3) and 1.17 (95 % CI: 0.92-1.50 per 10 mu g/m3), respectively. No statistically significant associations were observed between air pollution and mortality in other time windows. O3 showed an inverse association with mortality, while no association was observed between greenness and mortality. Adjusting for NDVI increased the hazard ratios for PM2.5, PM10, BC and NO2 exposures in 1990. We did not find significant interactions between greenness and air pollution metrics.Conclusion: Long term exposure to even low levels of air pollution is associated with mortality. Opening up for a long latency period, our findings indicate that air pollution exposures over time may be even more harmful than anticipated.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Arbetsmedicin och miljömedicin (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Occupational Health and Environmental Health (hsv//eng)
NATURVETENSKAP  -- Geovetenskap och miljövetenskap -- Miljövetenskap (hsv//swe)
NATURAL SCIENCES  -- Earth and Related Environmental Sciences -- Environmental Sciences (hsv//eng)

Nyckelord

Green space
Long-term effect
Nitrogen dioxide
Ozone
Particulate
matter
Premature mortality
urban street scale
regional-scale
follow-up
association
vegetation
forecasts
cities
cohort
women
men
Environmental Sciences & Ecology
Green space

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