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Bioimpedance techno...
Bioimpedance technology for detection of thoracic injury
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- Buendia, Ruben, 1982 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Candefjord, Stefan, 1981 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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Sanchez, B. (author)
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- Granhed, Hans (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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- Sjöqvist, Bengt-Arne, 1952 (author)
- Chalmers tekniska högskola,Chalmers University of Technology
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- Örtenwall, Per, 1951 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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- Caragounis, Eva Corina (author)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för kirurgi,Institute of Clinical Sciences, Department of Surgery
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(creator_code:org_t)
- 2017-10-31
- 2017
- English.
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In: Physiological Measurement. - : IOP Publishing. - 0967-3334 .- 1361-6579. ; 38:11, s. 2000-2014
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Abstract
Subject headings
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- Objective: Thoracic trauma is one of the most common and lethal types of injury, causing over a quarter of traumatic deaths. Severe thoracic injuries are often occult and difficult to diagnose in the field. There is a need for a point-of-care diagnostic device for severe thoracic injuries in the prehospital setting. Electrical bioimpedance (EBI) is non-invasive, portable, rapid and easy to use technology that can provide objective and quantitative diagnostic information for the prehospital environment. Here, we evaluated the performance of EBI to detect thoracic injuries. Approach: In this open study, EBI resistance (R), reactance (X) and phase angle (PA) of both sides of the thorax were measured at 50 kHz on patients suffering from thoracic injuries (n = 20). In parallel, a control group consisting of healthy subjects (n = 20) was recruited. A diagnostic mathematical algorithm, fed with input parameters derived from EBI data, was designed to differentiate patients from healthy controls. Main results: Ratios between the X and PA measurements of both sides of the thorax were significantly different (p < 0.05) between healthy volunteers and patients with left-and right-sided injuries. The diagnostic algorithm achieved a performance evaluated by leave-one-out cross-validation analysis and derived area under the receiver operating characteristic curve of 0.88. Significance: A diagnostic algorithm that accurately discriminates between patients suffering thoracic injuries and healthy subjects was designed using EBI technology. A larger, prospective and blinded study is thus warranted to validate the feasibility of EBI technology as a prehospital tool.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kirurgi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Surgery (hsv//eng)
- TEKNIK OCH TEKNOLOGIER -- Medicinteknik -- Medicinsk laboratorie- och mätteknik (hsv//swe)
- ENGINEERING AND TECHNOLOGY -- Medical Engineering -- Medical Laboratory and Measurements Technologies (hsv//eng)
Keyword
- bioimpedance
- thoracic injuries
- prehospital care
- diagnostics
- trauma
- injury prevention
- bioelectrical-impedance
- body-composition
- localized bioimpedance
- skin
- temperature
- muscle injury
- global burden
- trauma-center
- mortality
- deaths
- time
- Biophysics
- Engineering
- Physiology
- trauma
Publication and Content Type
- ref (subject category)
- art (subject category)
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