Self-assessed remission rates after electroconvulsive therapy of depressive disorders

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Brus, Ole,1982-Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology and Biostatistics,Örebro University, Sweden (author)

Self-assessed remission rates after electroconvulsive therapy of depressive disorders

Article/chapterEnglish2017

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2020-03-23
Cambridge University Press (CUP),2017

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LIBRIS-ID:oai:gup.ub.gu.se/259929
https://gup.ub.gu.se/publication/259929URI
https://doi.org/10.1016/j.eurpsy.2017.06.015DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-61681URI
http://kipublications.ki.se/Default.aspx?queryparsed=id:136972617URI
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-143103URI

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Language:English

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

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Funding Agency:Region Örebro county
Funding Agencies|Region Orebro county; Swedish research council [523-2013-2982]; Swedish foundation for strategic research [KF10-0039]
Background Electroconvulsive therapy (ECT) effectively treats severe depression, but not all patients remit. The aim of the study was to identify clinical factors that associate with ECT-induced remission in a community setting. Methods Depressed patients who underwent ECT in 2011–2014 were identified from the Swedish National Quality Register for ECT. Remission was defined as self-rated Montgomery-Åsberg Depression Rating Scale scores of 0–10 after ECT. Other registers provided data on previous antidepressant use, comorbidities, and demographics. Results Of 1671 patients fulfilling the inclusion criteria, 42.8% achieved remission. Older age, education length over 9 years, psychotic symptoms, shorter duration of preceding antidepressant use, pulse width stimulus ≥ 0.50 ms, absence of substance use disorders, anxiety diagnosis, lamotrigine, and benzodiazepines, were associated with remission. Conclusions This study shows that psychotic subtype of depression and older age are clinically relevant predictors of a beneficial ECT effect. Additionally, ECT outcomes can be further improved by optimizing the treatment technique and concomitant medication. © 2017 The Author(s)

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Neurovetenskaper hsv//swe
MEDICAL AND HEALTH SCIENCES Basic Medicine Neurosciences hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Psykiatri hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Psychiatry hsv//eng
ECT
Mania and bipolar disorder
Unipolar depression
Mania and bipolar disorder; Unipolar depression; ECT

Added entries (persons, corporate bodies, meetings, titles ...)

Cao, Yang,1972-Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden,Clinical Epidemiology and Biostatistics,Örebro University, Sweden; Karolinska Institute, Sweden(Swepub:oru)yco (author)
Gustafsson, E.Department of Psychiatry, Umeå University Hospital, Umeå, Sweden (author)
Hultén, M.Psychiatric Neuromodulation Unit (PNU), Department of Clinical Sciences Lund, Faculty of Medicine, Lund University, Lund, Sweden (author)
Landén, Mikael,1966Karolinska Institutet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi,Institute of Neuroscience and Physiology,Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden(Swepub:gu)xlandt (author)
Lundberg, J.Karolinska Institutet,Karolinska Institute, Sweden; Stockholm County Council, Sweden (author)
Nordanskog, Pia,1971-Linköpings universitet,Centrum för social och affektiv neurovetenskap,Medicinska fakulteten,Region Östergötland, Psykiatriska kliniken(Swepub:liu)piano33 (author)
Nordenskjöld, Axel,1977-Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Örebro University, Sweden(Swepub:oru)alnd (author)
Örebro universitetInstitutionen för medicinska vetenskaper (creator_code:org_t)

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In:European Psychiatry: Cambridge University Press (CUP)45, s. 154-1600924-93381778-3585

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By the author/editor: Brus, Ole, 1982-; Cao, Yang, 1972-; Gustafsson, E.; Hultén, M.; Landén, Mikael, ...; Lundberg, J.; show more...; Nordanskog, Pia, ...; Nordenskjöld, Ax ...; show less...

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