A longitudinal study on subjective sleep disturbance and risk of dementia in 85-year-olds followed over 15 years.

• Recent research indicates that sleep may play a role in the development of dementia. However, few studies have been conducted in the oldest-old ages. The aim of this study was to examinethe association between subjective sleep disturbance and incidentdementia in a population-based sample of 85-year-olds without dementia at baseline, followed until their death. Methods:Arepresen-tative sample of 85-year-olds (N¼494, 144 men, 350 women) were examined with comprehensive neuropsychiatric examinations. 147 individuals were excluded due to dementia at baseline, two subjects lacked data on subjective sleep disturbance, leaving 345 individuals. Sleep disturbance was assessed with a question regarding a subjective experience of decreased sleep during the last month while dementia during follow-up was diagnosed by geriatric psychiatrists according to DSM-III-R. Results: Subjective sleep disturbance at baseline wasnot related to incident dementia during follow-up (hazard ratio, 1.10; 95% CI, 0.77-1.59). Conclusions: We found in populations-based sample of 85-year-olds that subjective sleep disturbance was not related to incident dementia during follow-up. Future research need to elucidate whether sleep disturbance affect older individuals differently in younger compared to older ages.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Geriatrik (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Geriatrics (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Annan medicin och hälsovetenskap -- Gerontologi, medicinsk/hälsovetenskaplig inriktning (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Other Medical and Health Sciences -- Gerontology, specialising in Medical and Health Sciences (hsv//eng)

SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)

SOCIAL SCIENCES  -- Psychology (hsv//eng)

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