Care-related predictors for negative intrusive thoughts after prostate cancer diagnosisdata from the prospective LAPPRO trial

• ObjectiveNegative intrusive thoughts about one's prostate cancer have been associated with depressive mood and impaired quality of life among prostate cancer patients. However, little is known about possible predictors for negative intrusive thoughts among this group. We aimed to identify health- and care-related predictors for such thoughts among a population of men newly diagnosed with prostate cancer and undergoing radical prostatectomy. MethodsIn the LAPPRO-trial, 3154 men (80%) answered study-specific questionnaires at admission and 3months after surgery. Questions concerned socio-demographics, health, uncertainty, preparedness for symptoms, and the outcomenegative intrusive thoughts. Associations between variables were analyzed by log-binominal and multivariable approach. ResultsThe strongest predictor of negative intrusive thoughts at admission to surgery was uncertainty of cure, followed by binge drinking, poor physical health, antidepressant medication, not being prepared for urinary symptoms, age under 55, and physical pain. Reporting it not probable to obtain urinary symptoms after surgery lowered the odds. Negative intrusive thoughts before surgery were the strongest predictor for such thoughts 3months later followed by uncertainty of cure, physical pain, younger age, living alone, and poor self-reported physical health. ConclusionsOur findings showed an association of preoperative uncertainty of cure as well as low preparedness for well-known surgery-induced symptoms with higher occurrence of negative intrusive thoughts about prostate cancer. Future studies should examine if interventions designed to have healthcare professionals inform patients about their upcoming prostatectomy reduce patients' negative intrusive thoughts and thereby, improve their psychological well-being.

Subject headings

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Cancer och onkologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Cancer and Oncology (hsv//eng)

SAMHÄLLSVETENSKAP  -- Psykologi (hsv//swe)

SOCIAL SCIENCES  -- Psychology (hsv//eng)

SAMHÄLLSVETENSKAP  -- Psykologi -- Psykologi (hsv//swe)

SOCIAL SCIENCES  -- Psychology -- Psychology (hsv//eng)

MEDICIN OCH HÄLSOVETENSKAP  -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)

Keyword

clinical trial

intrusive thoughts

oncological sugery

prostate cancer

psychological well-being

quality-of-life

open radical prostatectomy

psychological distress

psychosocial stress

young men

depression

mortality

outcomes

anxiety

impact

Oncology

Psychology

Biomedical Social Sciences

Publication and Content Type

ref (subject category)

art (subject category)