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Long-term effects o...
Long-term effects of complications and vascular comorbidity in idiopathic normal pressure hydrocephalus: a quality registry study
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- Andrén, Kerstin, 1980 (författare)
- Umeå universitet,Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Klinisk neurovetenskap,Umeå universitet, Klinisk neurovetenskap, Sweden
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- Wikkelsö, Carsten, 1947 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Hydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Sweden
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- Sundström, Nina (författare)
- Umeå universitet,Radiofysik,Umeå universitet, Radiofysik, Sweden
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- Agerskov, Simon (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Hydrocephalus Research Unit, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Th
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- Israelsson, Hanna (författare)
- Umeå universitet,Klinisk neurovetenskap,Umeå universitet, Klinisk neurovetenskap, Sweden
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- Laurell, Katarina (författare)
- Umeå universitet,Klinisk neurovetenskap,Umeå universitet, Klinisk neurovetenskap, Sweden
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- Hellström, Per (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,nical Neuroscience, Institute of Neuroscience and Physiology, Th
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- Tullberg, Mats, 1965 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,nical Neuroscience, Institute of Neuroscience and Physiology, Th
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(creator_code:org_t)
- 2017-11-29
- 2018
- Engelska.
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Ingår i: Journal of Neurology. - : Springer Science and Business Media LLC. - 0340-5354 .- 1432-1459. ; 265:1, s. 178-186
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Abstract
Ämnesord
Stäng
- There is little knowledge about the factors influencing the long-term outcome after surgery for idiopathic normal pressure hydrocephalus (iNPH). To evaluate the effects of reoperation due to complications and of vascular comorbidity (hypertension, diabetes, stroke and heart disease) on the outcome in iNPH patients, 2-6 years after shunt surgery. We included 979 patients from the Swedish Hydrocephalus Quality Registry (SHQR), operated on for iNPH during 2004-2011. The patients were followed yearly by mailed questionnaires, including a self-assessed modified Rankin Scale (smRS) and a subjective comparison between their present and their preoperative health condition. The replies were grouped according to the length of follow-up after surgery. Data on clinical evaluations, vascular comorbidity, and reoperations were extracted from the SHQR. On the smRS, 40% (38-41) of the patients were improved 2-6 years after surgery and around 60% reported their general health condition to be better than preoperatively. Reoperation did not influence the outcome after 2-6 years. The presence of vascular comorbidity had no negative impact on the outcome after 2-6 years, assessed as improvement on the smRS or subjective improvement of the health condition, except after 6 years when patients with hypertension and a history of stroke showed a less favorable development on the smRS. This registry-based study shows no negative impact of complications and only minor effects of vascular comorbidity on the long-term outcome in iNPH.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Neurovetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Neurosciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Hydrocephalus
- Normal pressure
- Dementia
- Gait
- Complications
- Concomitant disease
- Risk factors
- shunt surgery
- risk-factors
- ventricular enlargement
- cerebrovascular-disease
- computed-tomography
- adult patients
- inph
- prevalence
- management
- Japan
- hydrocephalus
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Andrén, Kerstin, ...
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Wikkelsö, Carste ...
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Sundström, Nina
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Agerskov, Simon
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Israelsson, Hann ...
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Laurell, Katarin ...
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visa fler...
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Hellström, Per
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Tullberg, Mats, ...
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och Neurologi
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Göteborgs universitet
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Umeå universitet
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