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Patent Foramen Oval...
Patent Foramen Ovale and Cryptogenic Strokes in the Stroke in Young Fabry Patients Study.
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- Huber, Roman (författare)
- Clinical Center of Friedrichshafen
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- Grittner, Ulrike (författare)
- Charité - University Medicine Berlin
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- Weidemann, Frank (författare)
- Katharinen Hospital Unna
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- Thijs, Vincent (författare)
- Austin Health
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- Tanislav, Christian (författare)
- Justus Liebig University Giessen
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- Enzinger, Christian (författare)
- Medical University of Graz
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- Fazekas, Franz (författare)
- Medical University of Graz
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- Wolf, Markus (författare)
- University of Mannheim
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- Hennerici, Michael G (författare)
- University of Mannheim
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- McCabe, Dominick J H (författare)
- University College London
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- Putaala, Jukaa (författare)
- Helsinki University Central Hospital
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- Tatlisumak, Turgut (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för neurovetenskap och fysiologi, sektionen för klinisk neurovetenskap,Institute of Neuroscience and Physiology, Department of Clinical Neuroscience,Helsinki University Central Hospital
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- Kessler, Christoph (författare)
- University of Greifswald
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- von Sarnowski, Bettina (författare)
- University of Greifswald
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- Martus, Peter (författare)
- University of Tübingen
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- Kolodny, Edwin (författare)
- New York University
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- Norrving, Bo (författare)
- Lund University,Lunds universitet,Neurologi, Lund,Sektion IV,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Neurology, Lund,Section IV,Department of Clinical Sciences, Lund,Faculty of Medicine
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- Rolfs, Arndt (författare)
- University of Rostock
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(creator_code:org_t)
- 2017
- 2017
- Engelska.
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Ingår i: Stroke. - 1524-4628. ; 48:1, s. 30-35
- Relaterad länk:
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http://dx.doi.org/10...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- A patent foramen ovale (PFO) is disproportionately prevalent in patients with cryptogenic stroke. Without alternative explanations, it is frequently considered to be causative. A detailed stratification of these patients may improve the identification of incidental PFO.We investigated the PFO prevalence in 3497 transient ischemic attack and ischemic stroke patients aged 18 to 55 years in the prospective multicenter SIFAP1 study (Stroke in Young Fabry Patients 1) using the ASCO classification. Patients without an obvious cause for transient ischemic attack/stroke (ASCO 0) were divided into subgroups with and without vascular risk factors (ASCO 0+ and 0-). In addition, we looked for PFO-related magnetic resonance imaging lesion patterns.PFO was identified in 25% of patients. Twenty percent of patients with a definite or probable cause of transient ischemic attack/stroke (≥1 grade 1 or 2 ASCO criterion; n=1769) had a PFO compared with 29% of cryptogenic stroke patients (ASCO 0 and 3; n=1728; P<0,001); subdivision of cryptogenic strokes revealed a PFO in 24% of 978 ASCO 3 patients (n.s. versus ASCO 1 and 2) and a higher prevalence of 36% in 750 ASCO 0 cases (P<0.001 versus ASCO 3 and versus ASCO 1 and 2). PFO was more commonly observed in ASCO 0- (n=271) than in ASCO 0+ patients (n=479; 48 versus 29%; P<0.001). There was no PFO-associated magnetic resonance imaging lesion pattern.Cryptogenic stroke patients demonstrate a heterogeneous PFO prevalence. Even in case of less conclusive diseases like nonstenotic arteriosclerosis, patients should preferentially be considered to have a non-PFO-mediated stroke.URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Neurologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Neurology (hsv//eng)
Nyckelord
- Adolescent
- Adult
- Fabry Disease
- diagnostic imaging
- epidemiology
- Female
- Foramen Ovale
- Patent
- diagnostic imaging
- epidemiology
- Humans
- Ischemic Attack
- Transient
- diagnostic imaging
- epidemiology
- Male
- Middle Aged
- Prospective Studies
- Stroke
- diagnostic imaging
- epidemiology
- Young Adult
- arteriosclerosis
- ischemic stroke
- MRI
- patent foramen ovale
- risk factors
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
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Stroke
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Till lärosätets databas
- Av författaren/redakt...
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Huber, Roman
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Grittner, Ulrike
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Weidemann, Frank
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Thijs, Vincent
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Tanislav, Christ ...
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Enzinger, Christ ...
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Fazekas, Franz
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Wolf, Markus
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Hennerici, Micha ...
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McCabe, Dominick ...
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Putaala, Jukaa
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Tatlisumak, Turg ...
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Kessler, Christo ...
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von Sarnowski, B ...
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Martus, Peter
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Kolodny, Edwin
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Norrving, Bo
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Rolfs, Arndt
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- Om ämnet
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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och Neurologi
- Artiklar i publikationen
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Stroke
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Stroke: a journa ...
- Av lärosätet
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Göteborgs universitet
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Lunds universitet