Patients with unilateral transfemoral amputation treated with a percutaneous osseointegrated prosthesis. A cost-effectiveness analysis

Hansson, Elisabeth K,1954Gothenburg University,Göteborgs universitet,Institutionen för vårdvetenskap och hälsa,Institute of Health and Care Sciences (författare)

Aims: The aim of this study was to compare the cost-effectiveness of treatment with an osseointegrated percutaneous (OI-) prosthesis and a socket-suspended (S-) prosthesis for patients with a transfemoral amputation. Patients and Methods: A Markov model was developed to estimate the medical costs and changes in quality-adjusted life-years (QALYs) attributable to treatment of unilateral transfemoral amputation over a projected period of 20 years from a healthcare perspective. Data were collected alongside a prospective clinical study of 51 patients followed for two years. Results: OI-prostheses had an incremental cost per QALY gained of €83 374 compared with S-prostheses. The clinical improvement seen with OI-prostheses was reflected in QALYs gained. Results: were most sensitive to the utility value for both treatment arms. The impact of an annual decline in utility values of 1%, 2%, and 3%, for patients with S-prostheses resulted in a cost per QALY gained of €37 020, €24 662, and €18 952, respectively, over 20 years. Conclusion: From a healthcare perspective, treatment with an OI-prosthesis results in improved quality of life at a relatively high cost compared with that for S-prosthesis. When patients treated with S-prostheses had a decline in quality of life over time, the cost per QALY gained by OI-prosthesis treatment was considerably reduced.

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Hälso- och sjukvårdsorganisation, hälsopolitik och hälsoekonomi hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Health Care Service and Management, Health Policy and Services and Health Economy hsv//eng
adult
Article
computer assisted tomography
cost effectiveness analysis
device infection
device removal
female
follow up
human
leg amputation
major clinical study
male
medical record
osseointegration
patient-reported outcome
preoperative evaluation
priority journal
prospective study
prosthesis loosening
quality adjusted life year
quality control procedures
Short Form 36
skin penetration
surgical patient
transfemoral amputation
amputation
cost benefit analysis
devices
economics
femur
limb prosthesis
Markov chain
middle aged
outcome assessment
procedures
prosthesis implantation
quality of life
rehabilitation
surgery
Sweden
Artificial Limbs
Cost-Benefit Analysis
Follow-Up Studies
Humans
Markov Chains
Outcome Assessment (Health Care)
Prospective Studies
Quality-Adjusted Life Years

Hagberg, Kerstin,1957Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics(Swepub:gu)xhagbk (författare)
Cawson, M. (författare)
Brodtkorb, T. H. (författare)
Göteborgs universitetInstitutionen för vårdvetenskap och hälsa (creator_code:org_t)

Av författaren/redakt...: Hansson, Elisabe ...; Hagberg, Kerstin ...; Cawson, M.; Brodtkorb, T. H.

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Hälsovetenskap; och Hälso och sjukvå ...

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