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Left atrial velocit...
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Jarnert, C.Karolinska Institutet
(author)
Left atrial velocity vector imaging for the detection and quantification of left ventricular diastolic function in type 2 diabetes
- Article/chapterEnglish2008
Publisher, publication year, extent ...
Numbers
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LIBRIS-ID:oai:gup.ub.gu.se/267983
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https://gup.ub.gu.se/publication/267983URI
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https://doi.org/10.1016/j.ejheart.2008.08.012DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:117941381URI
Supplementary language notes
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Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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UNLABELLED: Left ventricular (LV) diastolic dysfunction (DD) is diagnosed by Doppler echocardiography (DE) and Tissue Doppler imaging (TDI). Velocity vector imaging (VVI) evaluates myocardial deformation (strain). We studied left atrial (LA) deformation and volumes by VVI in relation to established Doppler-derived indices of LV diastolic function in diabetic patients. MATERIAL: Using DE and TDI , 87 patients (males 49%; age 60+/-7 years) with type 2 diabetes mellitus were classified as having no (n=60), mild (n=13) or moderate (n=14) DD. RESULTS: LA volume was larger in moderate (72.3+/-22.4 ml) than in mild DD (58.8+/-16.1 ml; p=0.01) and no DD (57.9+/-16.0 ml; p=0.01). LA roof strain distinguished no DD from mild and moderate DD (p=0.0073). Systolic LA strain correlated to total emptying fraction (r=0.70, p<0.0001), and inversely to LA volume (r=-0.35, p=0.0009). A cross-validated analysis of no versus mild or moderate DD expressed by LA strain revealed a positive predictive value of 48% and negative of 84%. CONCLUSION: LA strain by VVI is impaired in patients with type 2 diabetes mellitus and mild or moderate LV DD. LA strain seems of value in distinguishing normal from abnormal diastolic function. VVI offers new information on regional LA function and LA volumes but has too limited discriminative power to detect early LV DD.
Subject headings and genre
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MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin hsv//swe
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MEDICAL AND HEALTH SCIENCES Clinical Medicine hsv//eng
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Atrial Function
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Left/*physiology
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Diabetes Mellitus
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Type 2/complications/*physiopathology
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Diastole
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Echocardiography
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Doppler/*methods
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Female
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Follow-Up Studies
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Heart Atria/*diagnostic imaging/physiopathology
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Humans
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Male
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Middle Aged
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Myocardial Contraction/*physiology
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Severity of Illness Index
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Ventricular Dysfunction
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Left/diagnostic imaging/etiology/*physiopathology
Added entries (persons, corporate bodies, meetings, titles ...)
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Melcher, A.Karolinska Institutet
(author)
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Caidahl, Kenneth,1949Karolinska Institutet,Gothenburg University,Göteborgs universitet,Extern,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,External,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xcaike
(author)
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Persson, H.Karolinska Institutet
(author)
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Ryden, L.Karolinska Institutet
(author)
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Eriksson, M. J.Karolinska Institutet
(author)
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Karolinska InstitutetExtern
(creator_code:org_t)
Related titles
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In:European Journal of Heart Failure: Wiley10:11, s. 1080-71388-9842
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