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  • Petersen, M. A. (author)

The EORTC CAT Core-The computer adaptive version of the EORTC QLQ-C30 questionnaire

  • Article/chapterEnglish2018

Publisher, publication year, extent ...

  • Elsevier BV,2018

Numbers

  • LIBRIS-ID:oai:gup.ub.gu.se/270155
  • https://gup.ub.gu.se/publication/270155URI
  • https://doi.org/10.1016/j.ejca.2018.04.016DOI

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  • Language:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Background: To optimise measurement precision, relevance to patients and flexibility, patient-reported outcome measures (PROMs) should ideally be adapted to the individual patient/study while retaining direct comparability of scores across patients/studies. This is achievable using item banks and computerised adaptive tests (CATs). The European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire Core 30 (QLQ-C30) is one of the most widely used PROMs in cancer research and clinical practice. Here we provide an overview of the research program to develop CAT versions of the QLQ-C30's 14 functional and symptom domains. Methods: The EORTC Quality of Life Group's strategy for developing CAT item banks consists of: literature search to identify potential candidate items; formulation of new items compatible with the QLQ-C30 item style; expert evaluations and patient interviews; field-testing and psychometric analyses, including factor analysis, item response theory calibration and simulation of measurement properties. In addition, software for setting up, running and scoring CAT has been developed. Results: Across eight rounds of data collections, 9782 patients were recruited from 12 countries for the field-testing. The four phases of development resulted in a total of 260 unique items across the 14 domains. Each item bank consists of 7-34 items. Psychometric evaluations indicated higher measurement precision and increased statistical power of the CAT measures compared to the QLQ-C30 scales. Using CAT, sample size requirements may be reduced by approximately 20-35% on average without loss of power. Conclusions: The EORTC CAT Core represents a more precise, powerful and flexible measurement system than the QLQ-C30. It is currently being validated in a large independent, international sample of cancer patients. (C) 2018 Elsevier Ltd. All rights reserved.

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  • Aaronson, N. K. (author)
  • Arraras, J. I. (author)
  • Chie, W. C. (author)
  • Conroy, T. (author)
  • Costantini, A. (author)
  • Dirven, L. (author)
  • Fayers, P. (author)
  • Gamper, E. M. (author)
  • Giesinger, J. M. (author)
  • Habets, E. J. J. (author)
  • Hammerlid, Eva,1957Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar,Institute of Clinical Sciences, Department of Otorhinolaryngology(Swepub:gu)xhamev (author)
  • Helbostad, J. (author)
  • Hjermstad, M. J. (author)
  • Holzner, B. (author)
  • Johnson, C. (author)
  • Kemmler, G. (author)
  • King, M. T. (author)
  • Kaasa, S. (author)
  • Loge, J. H. (author)
  • Reijneveld, J. C. (author)
  • Singer, S. (author)
  • Taphoorn, M. J. B. (author)
  • Thamsborg, L. H. (author)
  • Tomaszewski, K. A. (author)
  • Velikova, G. (author)
  • Verdonck-de Leeuw, I. M. (author)
  • Young, T. (author)
  • Groenvold, M. (author)
  • European Org Res Treatment, Cancer (author)
  • Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för öron-, näs- och halssjukdomar (creator_code:org_t)

Related titles

  • In:European Journal of Cancer: Elsevier BV100, s. 8-160959-8049

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