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Adjunctive local an...
Adjunctive local antibiotic therapy in the treatment of peri-implantitis II : clinical and radiographic outcomes.
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- Salvi, Giovanni E (författare)
- School of Dental Medicine, University of Berne, Berne, Switzerland
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- Persson, G. Rutger (författare)
- School of Dental Medicine, University of Berne, Berne, Switzerland
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- Heitz-Mayfield, Lisa J A (författare)
- University of Western Australia, Perth, Australia
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visa fler...
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- Frei, Marc (författare)
- School of Dental Medicine, University of Berne, Berne, Switzerland
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- Lang, Niklaus P (författare)
- School of Dental Medicine, University of Berne, Berne, Switzerland
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visa färre...
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(creator_code:org_t)
- 2007
- 2007
- Engelska.
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Ingår i: Clinical Oral Implants Research. - 0905-7161 .- 1600-0501. ; 18:3, s. 281-285
- Relaterad länk:
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https://doi.org/10.1...
Abstract
Ämnesord
Stäng
- AIM: To monitor over 12 months clinical and radiographic changes occurring after adjunctive local delivery of minocycline microspheres for the treatment of peri-implantitis.MATERIAL AND METHODS: In 25 partially edentulous subjects, 31 implants diagnosed with peri-implantitis were treated. Three weeks after oral hygiene instruction, mechanical debridement and local antiseptic cleansing using 0.2% chlorhexidine gel, baseline (Day 0) parameters were recorded. Minocycline microspheres (Arestin) were locally delivered to each implant site with bone loss and a probing pocket depth (PPD) >or=5 mm. Rescue therapy with Arestin was allowed at Days 180 and 270 at any site exhibiting an increase in PPD>or=2 mm from the previous visit. The following clinical parameters were recorded at four sites/implant at Day 0, 10, 30, 60, 90, 180, 270 and 360: PPD, clinical attachment level (CAL), bleeding on probing (BOP) and plaque index (PlI).RESULTS: Six implants in six subjects were either rescued or exited because of persisting active peri-implantitis. Successful implants showed a statistically significant reduction in both PPD and percentage of sites with BOP between baseline and Day 360 (P<0.05). At mesial implant sites, the mean PPD reduction amounted to 1.6 mm (95% CI: 0.9-2.2 mm, P<0.001) and was accompanied by a statistically significant reduction of the BOP value (P<0.001). Binary regression analysis showed that the clinical parameters and smoking history could not discriminate between successfully treated and rescued or exited implants at any observation time point.CONCLUSION: Non-surgical mechanical treatment of peri-implantitis lesions with adjunctive local delivery of microencapsulated minocycline led to positive effects on clinical parameters up to 12 months.
Ämnesord
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dentistry (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Odontologi (hsv//swe)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
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