(WFRF:(Wolfgang Andreas 1977)) srt2:(2005-2009)
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- Robinson, Yohan,1977Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för ortopedi,Institute of Clinical Sciences, Department of Orthopaedics,Charité – Campus Benjamin Franklin, Klinik für Unfall- und Wiederherstellungschirurgie, Berlin (author)
Erythropoiesis in multiply injured patients.
- Article/chapterEnglish2006
Publisher, publication year, extent ...
- Ovid Technologies (Wolters Kluwer Health),2006
Numbers
- LIBRIS-ID:oai:gup.ub.gu.se/277406
- https://gup.ub.gu.se/publication/277406URI
- https://doi.org/10.1097/01.ta.0000240969.13891.9bDOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-170591URI
Supplementary language notes
- Language:English
Part of subdatabase
- SwePubSwePub
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Notes
- Posttraumatic anemia in multiply injured patients is caused by hemorrhage, reduced red blood cell survival, and impaired erythropoiesis. Trauma-induced hyperinflammation causes impaired bone-marrow function by means of blunted erythropoietin (EPO) response, reduced iron availability, suppression and egress of erythroid progenitor cells. To treat posttraumatic anemia in severely injured patients, symptomatic therapy by blood transfusion is not sufficient. Furthermore, EPO, iron, and the use of red cell substitutes should be considered. The posttraumatic systemic inflammatory response syndrome (SIRS) induces posttraumatic anemia. Thus, a worsening of SIRS by a "second-hit" through blood transfusion ought to be avoided.
Subject headings and genre
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Kirurgi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Surgery hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Ortopedi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Orthopaedics hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Anestesi och intensivvård hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Anesthesiology and Intensive Care hsv//eng
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Hematologi hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Hematology hsv//eng
- Anemia
- etiology
- Erythrocyte Transfusion
- Erythrocytes
- pathology
- Erythropoiesis
- physiology
- Fluid Therapy
- Hemorrhage
- complications
- Humans
- Iron
- deficiency
- physiology
- Multiple Trauma
- physiopathology
- Resuscitation
- methods
- Systemic Inflammatory Response Syndrome
- physiopathology
- trauma
Added entries (persons, corporate bodies, meetings, titles ...)
- Hostmann, Arwed (author)
- Matenov, Alexander (author)
- Ertel, Wolfgang (author)
- Oberholzer, Andreas (author)
- Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för ortopedi (creator_code:org_t)
Related titles
- In:The Journal of trauma: Ovid Technologies (Wolters Kluwer Health)61:5, s. 1285-910022-52821529-8809
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