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- Doria, A S (författare)
Reliability and construct validity of the compatible MRI scoring system for evaluation of elbows in haemophilic children.
- Artikel/kapitelEngelska2008
Förlag, utgivningsår, omfång ...
- Wiley,2008
Nummerbeteckningar
- LIBRIS-ID:oai:lup.lub.lu.se:8533420a-a130-4483-b35a-ab9bf07c2e59
- https://lup.lub.lu.se/record/1144752URI
- https://doi.org/10.1111/j.1365-2516.2007.01602.xDOI
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- Språk:engelska
- Sammanfattning på:engelska
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- SwePubSwePub
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- Summary. We assessed the reliability and construct validity of the Compatible MRI scale for evaluation of elbows, and compared the diagnostic performance of MRI and radiographs for assessment of these joints. Twenty-nine MR examinations of elbows from 27 boys with haemophilia A and B [age range, 5–17 years (mean, 11.5)] were independently read by four blinded radiologists on two occasions. Three centres participated in the study: (Toronto, n = 24 examinations; Atlanta, n = 3; Cuiaba, n = 2). The number of previous joint bleeds and severity of haemophilia were reference standard measures. The inter-reader reliability of MRI scores was substantial (ICC = 0.73) for the additive (A)-scale and excellent (ICC = 0.83) for the progressive (P)-scale. The intrareader reliability was excellent for both P-scores (ICC = 0.91) and A-scores (ICC = 0.93). The total P- and A-scores correlated poorly (r = 0.36) or moderately (r = 0.54), but positively, with clinical-laboratory measurements. The total MRI scores demonstrated high accuracy for discrimination of presence or absence of arthropathy [P-scale, area-under-the-curve (AUC) = 0.94 ± 0.05; A-scale, AUC = 0.89 ± 0.06], as did the soft tissue scores of both scales (P-scale, AUC = 0.90 ± 0.06; A-scale, AUC = 0.86 ± 0.06). Areas-under-the-curve used to discriminate severe disease demonstrated high accuracy for both P-MRI scores (AUC = 0.83 ± 0.09) and A-MRI scores (AUC = 0.87 ± 0.09), but non-diagnostic ability to discriminate mild disease. Similar results were noted for radiographic scales. In conclusion, both MRI scales demonstrated substantial to excellent reliability and accuracy for discrimination of presence/absence of arthropathy, and severe/non-severe disease, but poor to moderate convergent validity for total scores and non-diagnostic discriminant validity for mild/non-mild disease. Compared with radiographic scores, MRI scales did not perform better for discrimination of severity of arthropathy.
Ämnesord och genrebeteckningar
- MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Radiologi och bildbehandling hsv//swe
- MEDICAL AND HEALTH SCIENCES Clinical Medicine Radiology, Nuclear Medicine and Medical Imaging hsv//eng
- validity
- scoring systems
- reliability
- progressive
- magnetic resonance imaging
- haemophilia
- children
- arthropathy
- additive
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Lundin, BjörnLund University,Lunds universitet,Diagnostisk radiologi, Lund,Sektion V,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Diagnostic Radiology, (Lund),Section V,Department of Clinical Sciences, Lund,Faculty of Medicine(Swepub:lu)drad-blu (författare)
- Miller, S (författare)
- Kilcoyne, R (författare)
- Dunn, A (författare)
- Thomas, S (författare)
- Rivard, G (författare)
- Moineddin, R (författare)
- Babyn, P S (författare)
- Expert Imaging Working Group of the International Prophylaxis Study Group, and (författare)
- Diagnostisk radiologi, LundSektion V (creator_code:org_t)
Sammanhörande titlar
- Ingår i:Haemophilia: Wiley14:2, s. 303-3141351-82161365-2516
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