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Contact allergy to ...
Contact allergy to citral and its constituents geranial and neral, coupled with reactions to the prehapten and prohapten geraniol
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- Hagvall, Lina, 1978 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi,Institute of Clinical Sciences, Department of Dermatology and Venereology,Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Department of Dermatology and Venereology, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden
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- Bruze, Magnus (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Engfeldt, Malin (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Genetisk arbets- och miljömedicin,Occupational and Environmental Dermatology,Lund University Research Groups,Genetic Occupational and Environmental Medicine,Skåne University Hospital
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- Isaksson, Marléne (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Lindberg, Magnus, 1952- (författare)
- Örebro University,Örebro universitet,Institutionen för medicinska vetenskaper,Department of Dermatology, University Hospital, Örebro, Sweden
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- Ryberg, Kristina (författare)
- Department of Dermatology, Uddevalla Hospital, Uddevalla, Sweden,NU Hospital Group
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- Stenberg, Berndt (författare)
- Umeå University,Umeå universitet,Dermatologi och venereologi
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- Svedman, Cecilia (författare)
- Lund University,Lunds universitet,Yrkes- och miljödermatologi,Forskargrupper vid Lunds universitet,Occupational and Environmental Dermatology,Lund University Research Groups,Skåne University Hospital
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- Karlberg, Ann-Therese, 1947 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kemi och molekylärbiologi,Department of Chemistry and Molecular Biology,Department of Occupational and Environmental Dermatology, Lund University, Skåne University Hospital, Malmö, Sweden
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- Bråred Christensson, Johanna, 1965 (författare)
- University of Gothenburg,Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för dermatologi och venereologi,Institutionen för kemi och molekylärbiologi,Institute of Clinical Sciences, Department of Dermatology and Venereology,Department of Chemistry and Molecular Biology,Department of Dermatology and Venereology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Dermatochemistry and Skin Allergy, Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden
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(creator_code:org_t)
- 2019-11-06
- 2020
- Engelska.
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Ingår i: Contact Dermatitis. - : Wiley. - 0105-1873 .- 1600-0536. ; 82:1, s. 31-38
- Relaterad länk:
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http://dx.doi.org/10...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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https://lup.lub.lu.s...
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Abstract
Ämnesord
Stäng
- Background Citral is commonly used as a fragrance and flavor material and consists of the aldehydes geranial and neral. Citral is included in fragrance mix (FM) II. Geranial and neral have also been identified in autoxidation of geraniol, a fragrance compound present in FM I. Objectives To study contact allergy to citral, geranial, and neral, and concomitant reactivity to oxidized geraniol and fragrance markers of the baseline series. Methods A total of 1476 dermatitis patients with suspected allergic contact dermatitis were patch tested using geranial, neral, and citral, all 3.5% petrolatum (pet.) as well as geraniol 6.0% and oxidized geraniol 11% pet. in addition to the Swedish baseline series. Results Frequencies of positive reactions to citral, geranial, and neral were 2.9%, 3.4% and 1.9%, respectively. Together, citral and geranial gave 4.2% positive patch test reactions in consecutive dermatitis patients. In patients with positive reactions to citral or its components, 25% to 34% reacted to FM II and 61% reacted to oxidized geraniol. Conclusions Patch testing with citral, its components, or oxidized geraniol detects contact allergic reactions not detected using the baseline series. Patch testing with pure geraniol was shown to be of little value. Geranial and neral, although closely chemically related, are concluded to be separate haptens.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Dermatologi och venereologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Dermatology and Venereal Diseases (hsv//eng)
Nyckelord
- allergic contact dermatitis
- autoxidation
- citral
- fragrance mix I
- fragrance mix II
- geranial
- geraniol
- neral
- oxidized geraniol
- patch
- testing
- RRID
- SCR_001905
- cosmetic products
- oxidized limonene
- fragrance
- ingredients
- linalool
- exposure
- hydroperoxides
- multicenter
- sensitizers
- thoughts
- Allergic contact dermatitis
- patch testing
- RRID:SCR_001905
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Hagvall, Lina, 1 ...
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Bruze, Magnus
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Engfeldt, Malin
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Isaksson, Marlén ...
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Lindberg, Magnus ...
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Ryberg, Kristina
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visa fler...
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Stenberg, Berndt
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Svedman, Cecilia
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Karlberg, Ann-Th ...
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Bråred Christens ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Contact Dermatit ...
- Av lärosätet
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Göteborgs universitet
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Örebro universitet
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Umeå universitet
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Lunds universitet