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Impact of symptom s...
Impact of symptom severity in patients with diarrhoea-predominant irritable bowel syndrome (IBS-D): results from two separate surveys of HCPs and patients with IBS-D
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Emmanuel, A. (author)
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Goosey, R. W. (author)
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Wiseman, G. (author)
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Baker, S. (author)
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- Törnblom, Hans, 1966 (author)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
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(creator_code:org_t)
- 2020-04-26
- 2020
- English.
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In: BMC Gastroenterology. - : Springer Science and Business Media LLC. - 1471-230X. ; 20:1
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https://bmcgastroent...
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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Abstract
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- Background Management of diarrhoea-predominant irritable bowel syndrome (IBS-D) is generally based on patient-reported symptoms; however, limited information on symptom severity exists. The objective of the study was to assess the impact of IBS-D severity on patient burden and patient and healthcare professional attitudes towards IBS. Methods We conducted two web-based surveys of healthcare professionals and patients from Australia, Canada and Europe. We analysed patient characteristics and attitudes by IBS-D severity, which was assessed retrospectively using a composite of four variables: worst abdominal pain, IBS symptom frequency, Bristol Stool Form Scale and quality of life. Results Of 679 healthcare professional respondents, one-third routinely classified patients by severity. The patient survey was completed by 513 patients with mild (26%), moderate (33%) and severe (41%) IBS-D, classified using the composite scale. Age, sex and treatment satisfaction did not change with severity; however, 19% of patients classified with severe IBS-D agreed with the statement: 'When my IBS is bad, I wish I was dead' versus 4 and 7% of patients with mild and moderate IBS-D, respectively (p < 0.05). Significantly more patients classified with severe IBS-D reported medication use versus mild IBS-D. Conclusion Compared with milder symptoms, severe IBS-D was associated with increased medication use and a negative perspective of IBS-D. This highlights the need for a validated severity scale to inform treatment decisions.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Keyword
- Diarrhoea-predominant irritable bowel syndrome
- Gastrointestinal symptom
- rating scale
- IBS
- Outcomes research
- Patient-reported outcomes
- quality-of-life
- gastrointestinal symptoms
- disease severity
- education
- outcomes
- burden
- Gastroenterology & Hepatology
Publication and Content Type
- ref (subject category)
- art (subject category)
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