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International conse...
International consensus on the diagnosis and management of dumping syndrome
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- Scarpellini, E. (författare)
- Katholieke Univ Leuven, Translat Res Ctr Gastrointestinal Disorders TARGI, Dept Chron Dis Metab & Ageing ChroMetA, Leuven, Belgium.
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- Arts, J. (författare)
- St Lucas Hosp, Gastroenterol Div, Brugge, Belgium.
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- Karamanolis, G. (författare)
- Athens Univ, Attikon Univ Hosp, Hepatogastroenterol Unit, Dept Internal Med Propaedeut 2,Med Sch, Athens, Greece.
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- Laurenius, Anna (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för gastrokirurgisk forskning och utbildning,Institute of Clinical Sciences, Department of Gastrosurgical Research and Education,Univ Gothenburg, Sahlgrenska Acad, Dept Gastrosurg Res & Educ, Gothenburg, Sweden.
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- Siquini, W. (författare)
- Politech Univ Marche, Madonna Soccorso Gen Hosp, San Benedetto Tronto, Italy.
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- Suzuki, H. (författare)
- Tokai Univ, Dept Gastroenterol & Hepatol, Sch Med, Isehara, Kanagawa, Japan.
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- Ukleja, A. (författare)
- Harvard Med Sch, Beth Israel Deaconess Med Ctr, Div Gastroenterol, Boston, MA 02115 USA.
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- Van Beek, A. (författare)
- Univ Groningen, Univ Med Ctr Groningen, Dept Endocrinol, Groningen, Netherlands.
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- Vanuytsel, T. (författare)
- Katholieke Univ Leuven, Translat Res Ctr Gastrointestinal Disorders TARGI, Dept Chron Dis Metab & Ageing ChroMetA, Leuven, Belgium.
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- Bor, S. (författare)
- Ege Univ, Div Gastroenterol, Sch Med, Izmir, Turkey.
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- Ceppa, E. (författare)
- Indiana Univ Sch Med, Dept Surg, Indianapolis, IN 46202 USA.
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- Di Lorenzo, C. (författare)
- Nationwide Childrens Hosp, Div Pediat Gastroenterol, Columbus, OH USA.
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- Emous, M. (författare)
- Med Ctr Leeuwarden, Dept Bariatr & Metab Surg, Leeuwarden, Netherlands.
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- Hammer, H. (författare)
- Med Univ Graz, Dept Internal Med, Div Gastroenterol & Hepatol, Graz, Austria.
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- Hellström, Per M., 1954- (författare)
- Uppsala universitet,Gastroenterologi/hepatologi
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- Laville, M. (författare)
- Claude Bernard Univ, Dept Endocrinol, Lyon, France.
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- Lundell, L. (författare)
- Karolinska Institutet
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- Masclee, A. (författare)
- Univ Hosp Leiden, Dept Gastroenterol Hepatol, Leiden, Netherlands.
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- Ritz, P. (författare)
- INSERM, U1027, F-31073 Toulouse, France.
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- Tack, J. (författare)
- Katholieke Univ Leuven, Translat Res Ctr Gastrointestinal Disorders TARGI, Dept Chron Dis Metab & Ageing ChroMetA, Leuven, Belgium.
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Katholieke Univ Leuven, Translat Res Ctr Gastrointestinal Disorders TARGI, Dept Chron Dis Metab & Ageing ChroMetA, Leuven, Belgium St Lucas Hosp, Gastroenterol Div, Brugge, Belgium. (creator_code:org_t)
- 2020-05-26
- 2020
- Engelska.
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Ingår i: Nature Reviews Endocrinology. - : Springer Science and Business Media LLC. - 1759-5029 .- 1759-5037. ; 16:8, s. 448-466
- Relaterad länk:
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https://www.nature.c...
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https://doi.org/10.1...
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https://uu.diva-port... (primary) (Raw object)
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https://gup.ub.gu.se...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- Dumping syndrome is a common but underdiagnosed complication of gastric and oesophageal surgery. We initiated a Delphi consensus process with international multidisciplinary experts. We defined the scope, proposed statements and searched electronic databases to survey the literature. Eighteen experts participated in the literature summary and voting process evaluating 62 statements. We evaluated the quality of evidence using grading of recommendations assessment, development and evaluation (GRADE) criteria. Consensus (defined as >80% agreement) was reached for 33 of 62 statements, including the definition and symptom profile of dumping syndrome and its effect on quality of life. The panel agreed on the pathophysiological relevance of rapid passage of nutrients to the small bowel, on the role of decreased gastric volume capacity and release of glucagon-like peptide 1. Symptom recognition is crucial, and the modified oral glucose tolerance test, but not gastric emptying testing, is useful for diagnosis. An increase in haematocrit >3% or in pulse rate >10 bpm 30 min after the start of the glucose intake are diagnostic of early dumping syndrome, and a nadir hypoglycaemia level <50 mg/dl is diagnostic of late dumping syndrome. Dietary adjustment is the agreed first treatment step; acarbose is effective for late dumping syndrome symptoms and somatostatin analogues are preferred for patients who do not respond to diet adjustments and acarbose. Dumping syndrome is a frequent complication of oesophageal and gastric surgery, as well as bariatric surgery; however, guidance on how to manage patients with this condition is lacking. In this Evidence-based guideline, the authors use a Delphi consensus process to develop uniform guidance for the definition, diagnosis and management of dumping syndrome.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Gastroenterologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Gastroenterology and Hepatology (hsv//eng)
Nyckelord
- y gastric bypass
- quality-of-life
- vasoactive-intestinal-peptide
- hyperinsulinemic hypoglycemia
- somatostatin analog
- bariatric surgery
- postprandial hypoglycemia
- weight-loss
- reactive hypoglycemia
- octreotide-therapy
- Endocrinology & Metabolism
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- art (ämneskategori)
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Till lärosätets databas
- Av författaren/redakt...
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Scarpellini, E.
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Arts, J.
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Karamanolis, G.
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Laurenius, Anna
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Siquini, W.
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Suzuki, H.
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visa fler...
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Ukleja, A.
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Van Beek, A.
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Vanuytsel, T.
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Bor, S.
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Ceppa, E.
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Di Lorenzo, C.
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Emous, M.
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Hammer, H.
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Hellström, Per M ...
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Laville, M.
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Lundell, L.
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Masclee, A.
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Ritz, P.
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Tack, J.
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Endokrinologi oc ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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och Gastroenterologi
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Göteborgs universitet
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Uppsala universitet
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Karolinska Institutet