SwePub
Sök i LIBRIS databas

  Utökad sökning

WFRF:(Mellström K)
 

Sökning: WFRF:(Mellström K) > Putative Cut-Points...

  • Cawthon, P. M.Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA.;Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA.,California Pacific Medical Center,University of California, San Francisco (författare)

Putative Cut-Points in Sarcopenia Components and Incident Adverse Health Outcomes: AnSDOCAnalysis

  • Artikel/kapitelEngelska2020

Förlag, utgivningsår, omfång ...

  • 2020-07-07
  • Wiley,2020

Nummerbeteckningar

  • LIBRIS-ID:oai:gup.ub.gu.se/294913
  • https://gup.ub.gu.se/publication/294913URI
  • https://doi.org/10.1111/jgs.16517DOI
  • https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-419658URI
  • https://lup.lub.lu.se/record/a67066a7-a6ec-433e-9a51-eaa1817bce78URI

Kompletterande språkuppgifter

  • Språk:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • OBJECTIVES Analyses performed by the Sarcopenia Definitions and Outcomes Consortium (SDOC) identified cut-points in several metrics of grip strength for consideration in a definition of sarcopenia. We describe the associations between the SDOC-identified metrics of low grip strength (absolute or standardized to body size/composition); low dual-energy x-ray absorptiometry (DXA) lean mass as previously defined in the literature (appendicular lean mass [ALM]/ht(2)); and slowness (walking speed <.8 m/s) with subsequent adverse outcomes (falls, hip fractures, mobility limitation, and mortality). DESIGN Individual-level, sex-stratified pooled analysis. We calculated odds ratios (ORs) or hazard ratios (HRs) for incident falls, mobility limitation, hip fractures, and mortality. Follow-up time ranged from 1 year for falls to 8.8 +/- 2.3 years for mortality. SETTING Eight prospective observational cohort studies. PARTICIPANTS A total of 13,421 community-dwelling men and 4,828 community-dwelling women. MEASUREMENTS Grip strength by hand dynamometry, gait speed, and lean mass by DXA. RESULTS Low grip strength (absolute or standardized to body size/composition) was associated with incident outcomes, usually independently of slowness, in both men and women. ORs and HRs generally ranged from 1.2 to 3.0 for those below vs above the cut-point. DXA lean mass was not consistently associated with these outcomes. When considered together, those who had both muscle weakness by absolute grip strength (<35.5 kg in men and <20 kg in women) and slowness were consistently more likely to have a fall, hip fracture, mobility limitation, or die than those without either slowness or muscle weakness. CONCLUSION Older men and women with both muscle weakness and slowness have a higher likelihood of adverse health outcomes. These results support the inclusion of grip strength and walking speed as components in a summary definition of sarcopenia.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Manini, T.Univ Florida, Gainesville, FL USA.,University of Florida (författare)
  • Patel, S. M.Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA.,NIA, Longitudinal Studies Sect, Baltimore, MD 21224 USA.,California Pacific Medical Center,National Institute on Aging, United States (författare)
  • Newman, A.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA.,University of Pittsburgh (författare)
  • Travison, T.Beth Israel Deaconess Med Ctr, Dept Med, Marcus Inst Aging Res, Hebrew SeniorLife, Boston, MA 02215 USA.;Harvard Med Sch, Boston, MA 02115 USA.,Harvard Medical School (författare)
  • Kiel, D. P.Beth Israel Deaconess Med Ctr, Dept Med, Marcus Inst Aging Res, Hebrew SeniorLife, Boston, MA 02215 USA.;Harvard Med Sch, Boston, MA 02115 USA.,Harvard Medical School (författare)
  • Santanasto, A. J.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA.,University of Pittsburgh (författare)
  • Ensrud, K. E.Minneapolis VA Hlth Care Syst, Ctr Chron Dis Outcomes Res, Minneapolis, MN USA.;Univ Minnesota, Div Epidemiol & Community Hlth, Minneapolis, MN USA.;Univ Minnesota, Dept Med, Box 736 UMHC, Minneapolis, MN 55455 USA.,University of Minnesota (författare)
  • Xue, Q. L.Johns Hopkins Med Inst, Div Geriatr Med & Gerontol, Baltimore, MD 21205 USA.;Johns Hopkins Med Inst, Ctr Aging & Hlth, Baltimore, MD 21205 USA.,Johns Hopkins Hospital (författare)
  • Shardell, M. (författare)
  • Duchowny, K.Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA.,University of California, San Francisco (författare)
  • Karlsson, MagnusLund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups(Swepub:lu)orto-mka (författare)
  • Pencina, K. M.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA.,University of Pittsburgh (författare)
  • Fielding, R. A.Tufts Univ, Jean Mayer US Dept Agr Human Nutr Res Ctr Aging, Nutr Exercise Physiol & Sarcopenia Lab, Boston, MA 02111 USA.,Tufts University (författare)
  • Magaziner, J.Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA.,Slotervaart Hospital (författare)
  • Kwok, T.Chinese Univ Hong Kong, Dept Med & Therapeut, Fac Med, Shatin, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Sch Publ Hlth, Fac Med, Shatin, Hong Kong, Peoples R China.,Chinese University of Hong Kong (författare)
  • Karlsson, M. (författare)
  • Ohlsson, Claes,1965Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Ctr Bone & Arthrit Res, Dept Internal Med & Clin Nutr,Inst Med, Gothenburg, Sweden.,Sahlgrenska Academy(Swepub:gu)xohlcl (författare)
  • Mellström, Dan,1945Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Ctr Bone & Arthrit Res, Dept Internal Med & Clin Nutr,Inst Med, Gothenburg, Sweden.,Sahlgrenska Academy(Swepub:gu)xmelda (författare)
  • Hirani, V.Univ Sydney, Charles Perkins Ctr, Sydney, NSW, Australia.,University of Sydney (författare)
  • Ribom, Eva LUppsala University,Uppsala universitet,Ortopedi(Swepub:uu)evlri676 (författare)
  • Correa-de-Araujo, R.NIA, Bethesda, MD 20892 USA. (författare)
  • Bhasin, S.Harvard Med Sch, Boston Claude D Pepper Older Americans Independen, Brigham & Womens Hosp, Boston, MA 02115 USA.,Harvard Medical School (författare)
  • Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA.;Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA.California Pacific Medical Center (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Journal of the American Geriatrics Society: Wiley68:7, s. 1429-14370002-86141532-5415

Internetlänk

Hitta via bibliotek

Till lärosätets databas

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

 
pil uppåt Stäng

Kopiera och spara länken för att återkomma till aktuell vy