Sökning: WFRF:(Mellström K) >
Putative Cut-Points...
-
Cawthon, P. M.Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA.;Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA.,California Pacific Medical Center,University of California, San Francisco
(författare)
Putative Cut-Points in Sarcopenia Components and Incident Adverse Health Outcomes: AnSDOCAnalysis
- Artikel/kapitelEngelska2020
Förlag, utgivningsår, omfång ...
Nummerbeteckningar
-
LIBRIS-ID:oai:gup.ub.gu.se/294913
-
https://gup.ub.gu.se/publication/294913URI
-
https://doi.org/10.1111/jgs.16517DOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-419658URI
-
https://lup.lub.lu.se/record/a67066a7-a6ec-433e-9a51-eaa1817bce78URI
Kompletterande språkuppgifter
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
OBJECTIVES Analyses performed by the Sarcopenia Definitions and Outcomes Consortium (SDOC) identified cut-points in several metrics of grip strength for consideration in a definition of sarcopenia. We describe the associations between the SDOC-identified metrics of low grip strength (absolute or standardized to body size/composition); low dual-energy x-ray absorptiometry (DXA) lean mass as previously defined in the literature (appendicular lean mass [ALM]/ht(2)); and slowness (walking speed <.8 m/s) with subsequent adverse outcomes (falls, hip fractures, mobility limitation, and mortality). DESIGN Individual-level, sex-stratified pooled analysis. We calculated odds ratios (ORs) or hazard ratios (HRs) for incident falls, mobility limitation, hip fractures, and mortality. Follow-up time ranged from 1 year for falls to 8.8 +/- 2.3 years for mortality. SETTING Eight prospective observational cohort studies. PARTICIPANTS A total of 13,421 community-dwelling men and 4,828 community-dwelling women. MEASUREMENTS Grip strength by hand dynamometry, gait speed, and lean mass by DXA. RESULTS Low grip strength (absolute or standardized to body size/composition) was associated with incident outcomes, usually independently of slowness, in both men and women. ORs and HRs generally ranged from 1.2 to 3.0 for those below vs above the cut-point. DXA lean mass was not consistently associated with these outcomes. When considered together, those who had both muscle weakness by absolute grip strength (<35.5 kg in men and <20 kg in women) and slowness were consistently more likely to have a fall, hip fracture, mobility limitation, or die than those without either slowness or muscle weakness. CONCLUSION Older men and women with both muscle weakness and slowness have a higher likelihood of adverse health outcomes. These results support the inclusion of grip strength and walking speed as components in a summary definition of sarcopenia.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Manini, T.Univ Florida, Gainesville, FL USA.,University of Florida
(författare)
-
Patel, S. M.Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA.,NIA, Longitudinal Studies Sect, Baltimore, MD 21224 USA.,California Pacific Medical Center,National Institute on Aging, United States
(författare)
-
Newman, A.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA.,University of Pittsburgh
(författare)
-
Travison, T.Beth Israel Deaconess Med Ctr, Dept Med, Marcus Inst Aging Res, Hebrew SeniorLife, Boston, MA 02215 USA.;Harvard Med Sch, Boston, MA 02115 USA.,Harvard Medical School
(författare)
-
Kiel, D. P.Beth Israel Deaconess Med Ctr, Dept Med, Marcus Inst Aging Res, Hebrew SeniorLife, Boston, MA 02215 USA.;Harvard Med Sch, Boston, MA 02115 USA.,Harvard Medical School
(författare)
-
Santanasto, A. J.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA.,University of Pittsburgh
(författare)
-
Ensrud, K. E.Minneapolis VA Hlth Care Syst, Ctr Chron Dis Outcomes Res, Minneapolis, MN USA.;Univ Minnesota, Div Epidemiol & Community Hlth, Minneapolis, MN USA.;Univ Minnesota, Dept Med, Box 736 UMHC, Minneapolis, MN 55455 USA.,University of Minnesota
(författare)
-
Xue, Q. L.Johns Hopkins Med Inst, Div Geriatr Med & Gerontol, Baltimore, MD 21205 USA.;Johns Hopkins Med Inst, Ctr Aging & Hlth, Baltimore, MD 21205 USA.,Johns Hopkins Hospital
(författare)
-
Shardell, M.
(författare)
-
Duchowny, K.Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA.,University of California, San Francisco
(författare)
-
Karlsson, MagnusLund University,Lunds universitet,Ortopedi - klinisk och molekylär osteoporosforskning,Forskargrupper vid Lunds universitet,Orthopedics - Clinical and Molecular Osteoporosis Research,Lund University Research Groups(Swepub:lu)orto-mka
(författare)
-
Pencina, K. M.Univ Pittsburgh, Dept Epidemiol, Pittsburgh, PA 15261 USA.,University of Pittsburgh
(författare)
-
Fielding, R. A.Tufts Univ, Jean Mayer US Dept Agr Human Nutr Res Ctr Aging, Nutr Exercise Physiol & Sarcopenia Lab, Boston, MA 02111 USA.,Tufts University
(författare)
-
Magaziner, J.Univ Maryland, Sch Med, Dept Epidemiol & Publ Hlth, Baltimore, MD 21201 USA.,Slotervaart Hospital
(författare)
-
Kwok, T.Chinese Univ Hong Kong, Dept Med & Therapeut, Fac Med, Shatin, Hong Kong, Peoples R China.;Chinese Univ Hong Kong, Sch Publ Hlth, Fac Med, Shatin, Hong Kong, Peoples R China.,Chinese University of Hong Kong
(författare)
-
Karlsson, M.
(författare)
-
Ohlsson, Claes,1965Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Ctr Bone & Arthrit Res, Dept Internal Med & Clin Nutr,Inst Med, Gothenburg, Sweden.,Sahlgrenska Academy(Swepub:gu)xohlcl
(författare)
-
Mellström, Dan,1945Gothenburg University,Göteborgs universitet,Centre for Bone and Arthritis Research,Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition,Institute of Medicine, Department of Internal Medicine and Clinical Nutrition,Univ Gothenburg, Sahlgrenska Acad, Ctr Bone & Arthrit Res, Dept Internal Med & Clin Nutr,Inst Med, Gothenburg, Sweden.,Sahlgrenska Academy(Swepub:gu)xmelda
(författare)
-
Hirani, V.Univ Sydney, Charles Perkins Ctr, Sydney, NSW, Australia.,University of Sydney
(författare)
-
Ribom, Eva LUppsala University,Uppsala universitet,Ortopedi(Swepub:uu)evlri676
(författare)
-
Correa-de-Araujo, R.NIA, Bethesda, MD 20892 USA.
(författare)
-
Bhasin, S.Harvard Med Sch, Boston Claude D Pepper Older Americans Independen, Brigham & Womens Hosp, Boston, MA 02115 USA.,Harvard Medical School
(författare)
-
Calif Pacific Med Ctr, Res Inst, San Francisco, CA USA.;Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA.California Pacific Medical Center
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Journal of the American Geriatrics Society: Wiley68:7, s. 1429-14370002-86141532-5415
Internetlänk
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Cawthon, P. M.
-
Manini, T.
-
Patel, S. M.
-
Newman, A.
-
Travison, T.
-
Kiel, D. P.
-
visa fler...
-
Santanasto, A. J ...
-
Ensrud, K. E.
-
Xue, Q. L.
-
Shardell, M.
-
Duchowny, K.
-
Karlsson, Magnus
-
Pencina, K. M.
-
Fielding, R. A.
-
Magaziner, J.
-
Kwok, T.
-
Karlsson, M.
-
Ohlsson, Claes, ...
-
Mellström, Dan, ...
-
Hirani, V.
-
Ribom, Eva L
-
Correa-de-Araujo ...
-
Bhasin, S.
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Geriatrik
- Artiklar i publikationen
-
Journal of the A ...
- Av lärosätet
-
Göteborgs universitet
-
Uppsala universitet
-
Lunds universitet